University Hospital Institutional Assessment Board (KUGH170208-001). Informed Consent Statement: Written
University Hospital Institutional Evaluation Board (KUGH170208-001). Informed Consent Statement: Written informed consent has been obtained from the patient(s) to publish this paper. Information Availability Statement: Not applicable. Conflicts of Interest: The authors declare no conflict of interest.Micromachines 2021, 12,15 of
applied sciencesReviewSalvia Species as Nutraceuticals: Concentrate on ML-SA1 Protocol antioxidant, Antidiabetic and Anti-Obesity PropertiesAndrea F. Afonso 1,two , Ol ia R. Pereira three, and Susana M. Cardoso 1, LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal; [email protected] Public Wellness Laboratory of Bragan , Neighborhood Wellness Unit, Rua Eng. Adelino Amaro da Costa, 5300-146 Bragan , Portugal Centro de Investiga o de Montanha (CIMO), Instituto Polit nico de Bragan , Campus de Santa Apol ia, 5300-253 Bragan , Portugal Correspondence: [email protected] (O.R.P.); [email protected] (S.M.C.); Tel.: +351-273-330-950 (O.R.P.)Abstract: Salvia plants belong to the Lamiaceae loved ones and are recognized as becoming strongly aromatic, getting broadly used for distinctive purposes in culinary or conventional medicine. These plants are effectively recognized as becoming rich in phenolic acids, flavonoids and terpenic compounds, which exhibit health-beneficial activities, safeguarding against oxidative and inflammatory-related ailments, like diabetes and obesity. Mainly because of those properties, phytochemicals from Salvia species have been investigated as well being advertising agents, for application in distinct fields. However, the increasing demand for all-natural products with achievable utilizes and applications in sector needs scientific validation research. This overview consists of a compilation of relevant research with an emphasis on the antioxidant, antidiabetic and anti-obesity properties of phenolic-rich extracts from Salvia plants. Search phrases: Salvia; polar extracts; phenolic compounds; antioxidant; antidiabetic; anti-obesityCitation: Afonso, A.F.; Pereira, O.R.; Cardoso, S.M. Salvia Species as Nutraceuticals: Concentrate on Antioxidant, Antidiabetic and Anti-Obesity Properties. Appl. Sci. 2021, 11, 9365. https://doi.org/10.3390/ app11209365 Academic Editor: Monica Gallo Received: six September 2021 BMS-986094 supplier Accepted: 4 October 2021 Published: 9 October1. Introduction There is a clear trend in customer preference towards natural food ingredients and additives which are perceived to be healthier [1]. It is effectively known that diet program supplementation with plant-based solutions wealthy in phytochemicals, like phenolic compounds [2,3], can supply a good influence on human health–reducing the risk of cancer, diabetes and inflammatory illnesses, and stopping neurodegenerative and cardiovascular program problems, among other people [4]. In this context, understanding in the bioactive prospective of unexplored plant secondary metabolites may perhaps grant the development of new plant-based functional foods, nutraceuticals and drugs [6,7]. Salvia would be the biggest genus inside the Lamiaceae family of plants, with over 900 species [8]. The name Salvia has its origin in the Latin word salvare, that means “healer”, in reference towards the curative properties of those plants, which have already been employed since ancient times as a medicinal herb [9,10]. The plants of this genus are distributed worldwide, though they are particularly prevalent in tropical and temperate regions of Europe around the Mediterranean region, in South-East Asia and in Central and South America [8,11]. They are mainly aromatic and perennial shrubs, with fl.