Recombinant Human IP-10 (CXCL10)
IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation. Additionally, it is angiostatic and mitogenic for vascular smooth muscle cells. Recombinant human IP-10 is an 8.6 kDa protein consisting of 77 amino acids including the four conserved cysteine residues present in CXC chemokines. Talarozole
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Source: |
E. Coli
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Purity:
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Above 98% as determined by SDS-PAGE Analysis.
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Cross Reactivity: |
Bacteria, Monkey, Mouse,Leech, Human + Hamster
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Biological Activity
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Determined by its ability to chemoattract human T-Lymphocytes using a concentration of 10-50 ng/ml.
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AA Sequence
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VPLSRTVRC TCISISNQP VNPRSLEKL EIIPASQFC PRVEIIATM KKKGEKRCL NPESKAIKN LLKAVSKER SKRSP
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| Research Interest: | , , , Inflammation, Proliferation and Cell Cycle, |
| Cell Type: | |
| Protein Cross Reactivity: | Bacteria, Monkey, Mouse,Leech, Human + Hamster |