Animal-Free Recombinant Human IGF-I


The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant human IGF-I and IGF-II are globular proteins containing 70 and 67 amino acids, respectively, and 3 intra-molecular disulfide bonds. Manufactured using all non-animal reagents.

Monomethyl auristatin E


Source:
E. Coli
&nbsp

Purity:
Above 98% as determined by SDS-PAGE Analysis.
&nbsp

Cross Reactivity:
Bacteria, Chicken, Cow, Frog, Horse, Monkey, Mouse, Pig, Rat, Sheep, Tiger Salamander
&nbsp

Biological Activity
The ED50 was determined by a cell proliferation assay using FDC-P1 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.
&nbsp

AA Sequence
GPETLCGAE LVDALQFVC GDRGFYFNK PTGYGSSSR RAPQTGIVD ECCFRSCDL RRLEMYCAP LKPAKSA
Research Interest: , , Inflammation, Proliferation and Cell Cycle,
Protein Cross Reactivity: Bacteria, Chicken, Cow, Frog, Horse, Monkey, Mouse, Pig, Rat, Sheep, Tiger Salamander

Availability: In stock

Size Price Qty
500µg

$215.00

1mg

$320.00

MED: 19059195

Animal-Free Recombinant Human IGF-I


The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant human IGF-I and IGF-II are globular proteins containing 70 and 67 amino acids, respectively, and 3 intra-molecular disulfide bonds. Manufactured using all non-animal reagents.

Palbociclib


Source:
E. Coli
&nbsp

Purity:
Above 98% as determined by SDS-PAGE Analysis.
&nbsp

Cross Reactivity:
Bacteria, Chicken, Cow, Frog, Horse, Monkey, Mouse, Pig, Rat, Sheep, Tiger Salamander
&nbsp

Biological Activity
The ED50 was determined by a cell proliferation assay using FDC-P1 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.
&nbsp

AA Sequence
GPETLCGAE LVDALQFVC GDRGFYFNK PTGYGSSSR RAPQTGIVD ECCFRSCDL RRLEMYCAP LKPAKSA
Research Interest: , , Inflammation, Proliferation and Cell Cycle,
Protein Cross Reactivity: Bacteria, Chicken, Cow, Frog, Horse, Monkey, Mouse, Pig, Rat, Sheep, Tiger Salamander

Availability: In stock

Size Price Qty
500µg

$215.00

1mg

$320.00

MED: 19064754

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