Animal-Free Recombinant Human KGF (FGF-7)
Keratinocyte Growth Factor (KGF/FGF-7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of variety of tissues, by promoting cellular proliferation and differentiation. KGF/FG-7 is a mitogen factor specific for epithelial cells and keratinocytes and signals through FGFR 2b. KGF/FGF-7 plays a role in kidney and lung development, angiogenesis, and wound healing. Recombinant human KGF/FGF-7 is an 18.9 kDa protein consisting of 163 amino acid residues. Manufactured using all non-animal reagents.
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Source: |
E. Coli
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Purity:
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Above 95% as determined by SDS-PAGE Analysis.
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Cross Reactivity: |
Mouse, Rat
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Biological Activity
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The ED50 as determined by the dose-dependent stimulation of thymidine uptake by KGF-responsive BaF3 cells is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg.
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AA Sequence
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CNDMTPEQM ATNVNCSSP ERHTRSYDY MEGGDIRVR RLFCRTQWY LRIDKRGKV KGTQEMKNN YNIMEIRTV AVGIVAIKG VESEFYLAM NKEGKLYAK KECNEDCNF KELILENHY NTYASAKWT HNGGEMFVA LNQKGIPVR GKKTKKEQK TAHFLPMAI T
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| Research Interest: | , , Proliferation and Cell Cycle |
| Protein Cross Reactivity: | Mouse, Rat |