Anti-Human CD57 SAFIRE Purified
The TBO1 monoclonal antibody specifically binds to human CD57, a 110 kDA glycoprotein expressed on a subset of natural killer lymphocytes, cells, neural cells and striated muscle. It is reported that the molecule is involved in cell-matrix interactions and is upregulated in some disease states. LGX820
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Clone
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TBO1
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Format: |
SAFIRE Purified
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Applications
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FC, FA
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Reactivity
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Human
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Isotype:
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Mouse IgM
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Preperation:
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The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
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Formulation:
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Phosphate-buffered aqueous solution, ph7.2.
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References:
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Palmer, B. E., Blyveis, N., Fontenot, A. P., & Wilson, C. C. (2005). Functional and phenotypic characterization of CD57+ CD4+ T cells and their association with HIV-1-induced T cell dysfunction. The Journal of Immunology, 175(12), 8415-8423. Schlossman, S. F. (1995). Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press. Prince, H. E., Kreiss, J. K., Kasper, C. K., Kleinman, S., Saunders, A. M., Waldbeser, L., … & Kaplan, H. S. (1985). Distinctive lymphocyte subpopulation abnormalities in patients with congenital coagulation disorders who exhibit lymph node enlargement. Blood, 66(1), 64-68. |