Anti-Human CD83 FITC


The HB15e monoclonal antibody specifically reacts with human CD83, a 43kDA single chain type I glycoprotein also known as HB15. A useful marker for mature human dendritic cells, it is also expressed on some activated lymphocytes. CD83’s precise role has not been deduced, but it is thought to be involved in antigen presentation. ALW-II-41-29

Clone
HB15e
Format:
FITC
Applications
FC
Reactivity
Human
Isotype:
Mouse IgG1, kappa
Research Interest:
Cell Type:
Preperation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Schlossman, S. F. (1995). Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

Zhou, L. J., Schwarting, R., Smith, H. M., & Tedder, T. F. (1992). A novel cell-surface molecule expressed by human interdigitating reticulum cells, Langerhans cells, and activated lymphocytes is a new member of the Ig superfamily. The Journal of Immunology149(2), 735-742.

Zhou, L. J., & Tedder, T. F. (1995). Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily. The Journal of Immunology154(8), 3821-3835.

MED: 19055209

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