Anti-Mouse Ly-6A/E (Sca-1) PE-Cyanine7
The D7 monoclonal antibody specifically reacts with mouse Ly-6A/E (Sca-1), a 18 kDa GPI-linked surface protein. It is expressed on multipotent hematopoietic stem cells (HSC) and subsets of B and T cells and involved in B and T cell lymphocyte responses. Splenocytes from Ly-6.2 strains exhibit a larger number of D7-positive cells than those from the Ly-6.1 strains. LY2109763
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Clone
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D7
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Format: |
PE-Cyanine7
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Applications
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FC
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Reactivity
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Mouse
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Isotype:
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Rat IgG2a, kappa
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Preperation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Ortega, G. U. S. T. A. V. O., Korty, P. E., Shevach, E. M., & Malek, T. R. (1986). Role of Ly-6 in lymphocyte activation. I. Characterization of a monoclonal antibody to a nonpolymorphic Ly-6 specificity. The Journal of Immunology, 137(10), 3240-3246. Malek, T. R., Ortega, G. U. S. T. A. V. O., Chan, C. H. R. I. S. T. I. N. A., Kroczek, R. A., & Shevach, E. M. (1986). Role of Ly-6 in lymphocyte activation. II. Induction of T cell activation by monoclonal anti-Ly-6 antibodies. The Journal of experimental medicine, 164(3), 709-722. Palfree, R. G., Dumont, F. J., & Hammerling, U. (1986). Ly-6A. 2 and Ly-6E. 1 molecules are antithetical and identical to MALA-1. Immunogenetics, 23(3), 197-207. |