Anti-Mouse CD90 (Thy-1) Purified
The G7 monoclonal antibody specifically reacts with mouse CD90, also known as thymus cell antigen-1 (Thy-1). CD90 is a 25-35 kDA GPI-anchored protein is the smallest member of the Ig superfamily. CD90 is expressed on thymocytes, neurons, hematopoietic stem cells, and T cells. It plays a role in T cell signal transduction and adhesion. The G7 antibody is reported to stimulate IL-2 secretion and T cell proliferation. OTX-017
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Clone
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G7
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Format: |
Purified
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Applications
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FC, IHC
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Reactivity
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Human
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Isotype:
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Rat IgG2c, kappa
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| Cell Type: | , , , |
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Preperation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Kruisbeek, A. M., Shevach, E., & Thornton, A. M. (2004). Proliferative assays for T cell function. Current protocols in immunology, 3-12. Nitta, H., Munger, W., Wilson, E., Ralston, R., & Alila, H. (1997). Improved in situ immunodetection of leukocytes on paraffin-embedded mouse spleen. Cell Vision, 4, 74-80. Gunter, K. C., Malek, T. R., & Shevach, E. M. (1984). T cell-activating properties of an anti-Thy-1 monoclonal antibody. Possible analogy to OKT3/Leu-4. The Journal of experimental medicine, 159(3), 716-730. |