Anti-Human GARP PE
The GARP5 monoclonal antibody specifically reacts with human Glycoprotein A Repetitions Predominant (GARP, also known as LRRC32 or Garpin) molecule, a 80 kDa transmembrane glycoprotein expressed on the cell surface. GARP is expressed in activated Treg cells, placenta, pancreas, liver, skeletal muscle, heart, lung, and kidney, and it acts as a receptor for latent TGF-β, which down-regulates the Treg cells action.
|
Clone
|
GARP5
|
|
Format: |
PE
|
|
Applications
|
FC
|
|
Reactivity
|
Human
|
|
Isotype:
|
Mouse IgG1
|
| Research Interest: | |
| Cell Type: | , |
|
Preperation:
|
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
|
|
Formulation:
|
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
|
|
References:
|
Wang, R., Zhu, J., Dong, X., Shi, M., Lu, C., & Springer, T. A. (2012). GARP regulates the bioavailability and activation of TGFβ. Molecular biology of the cell,23(6), 1129-1139. |