Autotaxin

Anti-Human CD3 PE-Cyanine7

By Autotaxin- autotaxin

Anti-Human CD3 PE-Cyanine7


The UCHT1 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.

Unlike HIT3a, another specific antibody of CD3, the UCHT1 antibody can stain both the surface and intracellular CD3ε. The immobilized UCHT1 can cross-link with the TCR complex, enhancing cellular activation and proliferation.

PSI-698

Clone
UCHT1
Format:
PE-Cyanine7
Applications
FC
Reactivity
Human
Isotype:
Mouse IgG1, kappa
Research Interest:
Cell Type: , , , Th17 cells
Preperation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

McMichael, A. J. (1987). Leucocyte typing III. Oxford University Press, Oxford. Norton AJ, Isaacson PG (1985)

Beverley, P. C., & Callard, R. E. (1981). Distinctive functional characteristics of human T lymphocytes defined by E rosetting or a monoclonal anti-T cell antibody. European journal of immunology, 11(4), 329-334.

MED: 19049967

Anti-Human CD3 PE-Cyanine7

By Autotaxin- autotaxin

Anti-Human CD3 PE-Cyanine7


The SK7 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction. The SK7 antibody is reported to have a mitogenic effect on the majority of peripheral blood T cells in the presence of functional monocytes. BAY 80-6947

Clone
SK7
Format:
PE-Cyanine7
Applications
FC
Reactivity
Human
Isotype:
Mouse IgG1, kappa
Research Interest:
Cell Type: , , , Th17 cells
Preperation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Van Dongen, J. J., Krissansen, G. W., Wolvers-Tettero, I. L., Comans-Bitter, W. M., Adriaansen, H. J., Hooijkaas, H., … & Terhorst, C. (1988). Cytoplasmic expression of the CD3 antigen as a diagnostic marker for immature T-cell malignancies. Blood, 71(3), 603-612.

Haynes, B. F. (1986). Summary of T cell studies performed during the second international workshop and conference on human leukocyte differentiation antigens. In Leukocyte typing II (pp. 3-30). Springer New York.

Kap, Y. S., van Meurs, M., van Driel, N., Koopman, G., Melief, M. J., Brok, H. P., … & At Hart, B. (2009). A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates. Journal of Histochemistry & Cytochemistry, 57(12), 1159-1167.

MED: 19049974

Anti-Human CD3 PE-Cyanine7

By Autotaxin- autotaxin

Anti-Human CD3 PE-Cyanine7


The OKT3 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.

The OKT3 antibody is an immunosuppressive, which has proven to be an effective therapeutic agent in liver, heart, and renal allograft rejection.

LDN-214118

Clone
OKT3
Format:
PE-Cyanine7
Applications
FC
Reactivity
Human
Isotype:
Mouse IgG2a, kappa
Research Interest:
Cell Type: , , , Th17 cells
Preperation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Schlossman, S., L. Bloumsell, et al. eds (1995). Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York

Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Adair, J. R., Athwal, D. S., Bodmer, M. W., Bright, S. M., Collins, A. M., Pulito, V. L., … & Jolliffe, L. K. (1994). Humanization of the murine anti-human CD3 monoclonal antibody OKT3. Human Antibodies, 5(1), 41-47.

Kap, Y. S., van Meurs, M., van Driel, N., Koopman, G., Melief, M. J., Brok, H. P., … & At Hart, B. (2009). A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates. Journal of Histochemistry & Cytochemistry, 57(12), 1159-1167.

MED: 19050011

Anti-Human CD3 PE-Cyanine7

By Autotaxin- autotaxin

Anti-Human CD3 PE-Cyanine7


The UCHT1 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.

Unlike HIT3a, another specific antibody of CD3, the UCHT1 antibody can stain both the surface and intracellular CD3ε. The immobilized UCHT1 can cross-link with the TCR complex, enhancing cellular activation and proliferation.

PSI-698

Clone
UCHT1
Format:
PE-Cyanine7
Applications
FC
Reactivity
Human
Isotype:
Mouse IgG1, kappa
Research Interest:
Cell Type: , , , Th17 cells
Preperation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

McMichael, A. J. (1987). Leucocyte typing III. Oxford University Press, Oxford. Norton AJ, Isaacson PG (1985)

Beverley, P. C., & Callard, R. E. (1981). Distinctive functional characteristics of human T lymphocytes defined by E rosetting or a monoclonal anti-T cell antibody. European journal of immunology, 11(4), 329-334.

MED: 19049967

Anti-Human CD3 PE-Cyanine7

By Autotaxin- autotaxin

Anti-Human CD3 PE-Cyanine7


The SK7 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction. The SK7 antibody is reported to have a mitogenic effect on the majority of peripheral blood T cells in the presence of functional monocytes. BAY 80-6947

Clone
SK7
Format:
PE-Cyanine7
Applications
FC
Reactivity
Human
Isotype:
Mouse IgG1, kappa
Research Interest:
Cell Type: , , , Th17 cells
Preperation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Van Dongen, J. J., Krissansen, G. W., Wolvers-Tettero, I. L., Comans-Bitter, W. M., Adriaansen, H. J., Hooijkaas, H., … & Terhorst, C. (1988). Cytoplasmic expression of the CD3 antigen as a diagnostic marker for immature T-cell malignancies. Blood, 71(3), 603-612.

Haynes, B. F. (1986). Summary of T cell studies performed during the second international workshop and conference on human leukocyte differentiation antigens. In Leukocyte typing II (pp. 3-30). Springer New York.

Kap, Y. S., van Meurs, M., van Driel, N., Koopman, G., Melief, M. J., Brok, H. P., … & At Hart, B. (2009). A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates. Journal of Histochemistry & Cytochemistry, 57(12), 1159-1167.

MED: 19049974

Anti-Human CD3 PE-Cyanine7

By Autotaxin- autotaxin

Anti-Human CD3 PE-Cyanine7


The OKT3 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.

The OKT3 antibody is an immunosuppressive, which has proven to be an effective therapeutic agent in liver, heart, and renal allograft rejection.

LDN-214118

Clone
OKT3
Format:
PE-Cyanine7
Applications
FC
Reactivity
Human
Isotype:
Mouse IgG2a, kappa
Research Interest:
Cell Type: , , , Th17 cells
Preperation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Schlossman, S., L. Bloumsell, et al. eds (1995). Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York

Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Adair, J. R., Athwal, D. S., Bodmer, M. W., Bright, S. M., Collins, A. M., Pulito, V. L., … & Jolliffe, L. K. (1994). Humanization of the murine anti-human CD3 monoclonal antibody OKT3. Human Antibodies, 5(1), 41-47.

Kap, Y. S., van Meurs, M., van Driel, N., Koopman, G., Melief, M. J., Brok, H. P., … & At Hart, B. (2009). A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates. Journal of Histochemistry & Cytochemistry, 57(12), 1159-1167.

MED: 19050011

By Autotaxin- autotaxin

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