Anti-Human CD79a PE
The HM47 monoclonal antibody reacts with the cytoplasmic domain of CD79a, a 47kDa type I integral membrane protein known as Iga or mb-1. It forms the part of the B-cell receptor complex with CD79b and is expressed on B cells from earliest pre-B to plasma cell stage. It is also reported that CD79a expresses weakly on myeloid cells and T cell precursors. CD79a is believed to be involved in transporting IgM to the surface of B cells. Vatalanib
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Clone
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HM47
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Format: |
PE
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Applications
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FC
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Reactivity
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Human, Mouse
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Isotype:
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Mouse IgG1, kappa
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Preperation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Mason, D. Y., Cordell, J. L., Tse, A. G., Van Dongen, J. J., Van Noesel, C. J., Micklem, K., … & Borst, J. (1991). The IgM-associated protein mb-1 as a marker of normal and neoplastic B cells. Journal of immunology (Baltimore, Md.: 1950), 147(11), 2474-2482. Bhargava, P., Kallakury, B. V., Ross, J. S., Azumi, N., & Bagg, A. (2007). CD79a is heterogeneously expressed in neoplastic and normal myeloid precursors and megakaryocytes in an antibody clone–dependent manner.American journal of clinical pathology, 128(2), 306-313. Hashimoto, M., Yamashita, Y., & Mori, N. (2002). Immunohistochemical detection of CD79a expression in precursor T cell lymphoblastic lymphoma/leukaemias. The Journal of pathology, 197(3), 341-347. |