Anti-Human CD123 APC
The 6H6 monoclonal antibody specifically reacts with human CD123, the alpha chain subunit of the IL-3 receptor. CD123’s affinity to IL-3 is low, but increases when associated with CD131. It can be found on basophils, dendritic cells, macrophages, and mast cells. Cot inhibitor-2
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Clone
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6H6
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Format: |
APC
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Applications
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FC
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Reactivity
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Human
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Isotype:
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Mouse IgG1, kappa
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| Research Interest: | , Cytokines & Growth Factors |
| Cell Type: | , |
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Preperation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Herling, M., Teitell, M. A., Shen, R. R., Medeiros, L. J., & Jones, D. (2003). TCL1 expression in plasmacytoid dendritic cells (DC2s) and the related CD4+ CD56+ blastic tumors of skin. Blood, 101(12), 5007-5009. Peduzzi, E., Groeper, C., Schütte, D., Zajac, P., Rondini, S., Mensah-Quainoo, E., … & Daubenberger, C. A. (2007). Local activation of the innate immune system in Buruli ulcer lesions. Journal of Investigative Dermatology, 127(3), 638-645. Sun, Q., Woodcock, J. M., Rapoport, A., Stomski, F. C., Korpelainen, E. I., Bagley, C. J., … & Lopez, A. F. (1996). Monoclonal antibody 7G3 recognizes the N-terminal domain of the human interleukin-3 (IL-3) receptor alpha-chain and functions as a specific IL-3 receptor antagonist. Blood, 87(1), 83-92. |