Anti-Human CD209 (DC-SIGN) PerCP-Cyanine5.5
The h209 monoclonal antibody reacts with human CD209, also known as Dendritic Cell-Specific Intercellular adhesion molecule 3 (ICAM-3)-Grabbing Nonintegrin (DC-SIGN). CD209 is a 44kDA type II membrane protein with a mannose-binding C-type lectin domain. It is reported to bind ICAM-2, ICAM-3, Butyrophilin, and HIV-1 gp120. CD209 is expressed on dendritic cells and is thought to mediate the endocytosis of pathogens, dendritic cell migration, and T cell proliferation. Rapamycin
|
Clone
|
h209
|
|
Format: |
PerCP-Cyanine5.5
|
|
Applications
|
FC
|
|
Reactivity
|
Human
|
|
Isotype:
|
Rat IgG2a, kappa
|
| Research Interest: | |
| Cell Type: | , |
|
Preperation:
|
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
|
|
Formulation:
|
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
|
|
References:
|
Kleijwegt, F. S., Laban, S., Duinkerken, G., Joosten, A. M., Koeleman, B. P., Nikolic, T., & Roep, B. O. (2011). Transfer of regulatory properties from tolerogenic to proinflammatory dendritic cells via induced autoreactive regulatory T cells. The Journal of Immunology, 187(12), 6357-6364. Wang, P., Yang, B., Zhou, B., Zhang, J., Li, S., Jiang, J., … & Jin, F. (2016). Distribution and expression profiles of dendritic cell subpopulations in human bladder cancer. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 9(7), 7180-7187. Pöhlmann, S., Baribaud, F., Lee, B., Leslie, G. J., Sanchez, M. D., Hiebenthal-Millow, K., … & Doms, R. W. (2001). DC-SIGN interactions with human immunodeficiency virus type 1 and 2 and simian immunodeficiency virus. Journal of Virology, 75(10), 4664-4672. |