Product Name :
SAFit1

Description:
SAFit1 is a FK506 binding protein 51 (FKBP51)-specific inhibitor with a Ki of 4±0.3 nM.

CAS:
1643125-32-9

Molecular Weight:
747.87

Formula:
C42H53NO11

Chemical Name:
2-{3-[(1R)-1-[(2S)-1-[(2S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carbonyloxy]-3-(3,4-dimethoxyphenyl)propyl]phenoxy}acetic acid

Smiles :
COC1C=C(C=C(OC)C=1OC)[C@H](C1CCCCC1)C(=O)N1CCCC[C@H]1C(=O)O[C@H](CCC1C=CC(OC)=C(C=1)OC)C1=CC(=CC=C1)OCC(O)=O

InChiKey:
OEQZPFWOEOOISR-AKTKKGGCSA-N

InChi :
InChI=1S/C42H53NO11/c1-48-34-20-18-27(22-35(34)49-2)17-19-33(29-14-11-15-31(23-29)53-26-38(44)45)54-42(47)32-16-9-10-21-43(32)41(46)39(28-12-7-6-8-13-28)30-24-36(50-3)40(52-5)37(25-30)51-4/h11,14-15,18,20,22-25,28,32-33,39H,6-10,12-13,16-17,19,21,26H2,1-5H3,(H,44,45)/t32-,33+,39-/m0/s1

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Vildagliptin} site|{Vildagliptin} Apoptosis|{Vildagliptin} Protocol|{Vildagliptin} Data Sheet|{Vildagliptin} supplier|{Vildagliptin} Cancer}

Additional information:
SAFit1 is a FK506 binding protein 51 (FKBP51)-specific inhibitor with a Ki of 4±0.{{Sodium metatungstate} web|{Sodium metatungstate} Apoptosis|{Sodium metatungstate} Activator|{Sodium metatungstate} Technical Information|{Sodium metatungstate} In stock|{Sodium metatungstate} supplier} 3 nM.|Product information|CAS Number: 1643125-32-9|Molecular Weight: 747.PMID:26644518 87|Formula: C42H53NO11|Chemical Name: 2-{3-[(1R)-1-[(2S)-1-[(2S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carbonyloxy]-3-(3,4-dimethoxyphenyl)propyl]phenoxy}acetic acid|Smiles: COC1C=C(C=C(OC)C=1OC)[C@H](C1CCCCC1)C(=O)N1CCCC[C@H]1C(=O)O[C@H](CCC1C=CC(OC)=C(C=1)OC)C1=CC(=CC=C1)OCC(O)=O|InChiKey: OEQZPFWOEOOISR-AKTKKGGCSA-N|InChi: InChI=1S/C42H53NO11/c1-48-34-20-18-27(22-35(34)49-2)17-19-33(29-14-11-15-31(23-29)53-26-38(44)45)54-42(47)32-16-9-10-21-43(32)41(46)39(28-12-7-6-8-13-28)30-24-36(50-3)40(52-5)37(25-30)51-4/h11,14-15,18,20,22-25,28,32-33,39H,6-10,12-13,16-17,19,21,26H2,1-5H3,(H,44,45)/t32-,33+,39-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : ≥ 300 mg/mL (401.14 mM).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|SAFit1 (1-1000 nM) potently stimulates neurite outgrowth in two neuronal cell lines (N2a and SH-SY5Y) as well as in primary hippocampal neurons. SAFit1 is active over a wide concentration range.|Products are for research use only. Not for human use.|

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