Product Name :
Nociceptin(1-7)
Description:
Nociceptin (1-7) is the N-terminal bioactive fragment of nociceptin (HY-P0183). Nociceptin (1-7) is a potent ORL1 (NOP) receptor agonist with antinociceptive activity. Nociceptin (1-7) combines with nociceptin reduces hyperalgesia in vivo.
CAS:
178249-42-8
Molecular Weight:
655.70
Formula:
C31H41N7O9
Chemical Name:
(2S)-2-{2-[(2S,3R)-2-[(2S)-2-(2-{2-[(2S)-2-amino-3-phenylpropanamido]acetamido}acetamido)-3-phenylpropanamido]-3-hydroxybutanamido]acetamido}propanoic acid
Smiles :
C[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)CC1C=CC=CC=1)[C@@H](C)O)C(O)=O
InChiKey:
KVTLKXLQUDUFSD-FLSSTNBBSA-N
InChi :
InChI=1S/C31H41N7O9/c1-18(31(46)47)36-25(41)17-35-30(45)27(19(2)39)38-29(44)23(14-21-11-7-4-8-12-21)37-26(42)16-33-24(40)15-34-28(43)22(32)13-20-9-5-3-6-10-20/h3-12,18-19,22-23,27,39H,13-17,32H2,1-2H3,(H,33,40)(H,34,43)(H,35,45)(H,36,41)(H,37,42)(H,38,44)(H,46,47)/t18-,19+,22-,23-,27-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Afatinib dimaleate} site|{Afatinib dimaleate} PI3K/Akt/mTOR|{Afatinib dimaleate} NF-κB|{Afatinib dimaleate} Purity & Documentation|{Afatinib dimaleate} In stock|{Afatinib dimaleate} manufacturer}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Nociceptin (1-7) is the N-terminal bioactive fragment of nociceptin (HY-P0183). Nociceptin (1-7) is a potent ORL1 (NOP) receptor agonist with antinociceptive activity. Nociceptin (1-7) combines with nociceptin reduces hyperalgesia in vivo.|Product information|CAS Number: 178249-42-8|Molecular Weight: 655.70|Formula: C31H41N7O9|Chemical Name: (2S)-2-{2-[(2S,3R)-2-[(2S)-2-(2-{2-[(2S)-2-amino-3-phenylpropanamido]acetamido}acetamido)-3-phenylpropanamido]-3-hydroxybutanamido]acetamido}propanoic acid|Smiles: C[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)CC1C=CC=CC=1)[C@@H](C)O)C(O)=O|InChiKey: KVTLKXLQUDUFSD-FLSSTNBBSA-N|InChi: InChI=1S/C31H41N7O9/c1-18(31(46)47)36-25(41)17-35-30(45)27(19(2)39)38-29(44)23(14-21-11-7-4-8-12-21)37-26(42)16-33-24(40)15-34-28(43)22(32)13-20-9-5-3-6-10-20/h3-12,18-19,22-23,27,39H,13-17,32H2,1-2H3,(H,33,40)(H,34,43)(H,35,45)(H,36,41)(H,37,42)(H,38,44)(H,46,47)/t18-,19+,22-,23-,27-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Ofatumumab} site|{Ofatumumab} Immunology/Inflammation|{Ofatumumab} Purity & Documentation|{Ofatumumab} Description|{Ofatumumab} manufacturer|{Ofatumumab} Epigenetics} |Shelf Life: ≥12 months if stored properly.PMID:24578169 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Nociceptin (1-7) (intrathecal injection; 150–1200 nmol; single dose) has no significant effect in the nociceptive thermal threshold (hyperalgesia). However, when nociceptin (1–7) is injected simultaneously with nociceptin (3.0 fmol), nociceptin-induced hyperalgesia is significantly reduced.|Products are for research use only. Not for human use.|