Anti-Human/Mouse IL-20 Receptor 2 (IL-20Rb) Purified
The 20RNTC monoclonal antibody specifically reacts with human and mouse interleukin-20 receptor 2 (IL-20R2 or IL-20Rb). IL-20R2 is a class II cytokine receptor that pairs with IL-20R to form a receptor capable of binding IL-19, IL-20, or IL-24 and binds IL-20, or IL-24 when paired with IL-22R1. It is primarily found on epithelial originated cells such as those found in the skin or intestines.
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Clone
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20RNTC
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Format: |
Purified
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Applications
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FC, WB, ICC
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Reactivity
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Human, Mouse
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Isotype:
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Rat IgG2a, kappa
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| Research Interest: | |
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Preperation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Blumberg, H., Conklin, D., Xu, W., Grossmann, A., Brender, T., Carollo, S., … & Chandrasekher, Y. A. (2001). Interleukin 20: discovery, receptor identification, and role in epidermal function. Cell, 104(1), 9-19. Wahl, C., Müller, W., Leithäuser, F., Adler, G., Oswald, F., Reimann, J., … & Wegenka, U. M. (2009). IL-20 receptor 2 signaling down-regulates antigen-specific T cell responses. The Journal of Immunology, 182(2), 802-810. Dumoutier, L., Leemans, C., Lejeune, D., Kotenko, S. V., & Renauld, J. C. (2001). Cutting edge: STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types. The Journal of Immunology, 167(7), 3545-3549. |