Anti-Mouse CD160 SAFIRE Purified
The CNX46-3 monoclonal antibody specifically binds to mouse CD160, a glycosyolphosphatidylinositol (GPI)-anchored membrane glycoprotein. It is reported to regulate NK cell activation and is expressed on a subset of T, NKT, NK cells, and all intestinal intraepithelial lymphocytes. CD160 broadly binds to classical and nonclassical MHC class I molecules. VT-464
|
Clone
|
CNX46-3
|
|
Format: |
SAFIRE Purified
|
|
Applications
|
FC, FA, IP, WB
|
|
Reactivity
|
Mouse
|
|
Isotype:
|
Rat IgG2a, kappa
|
| Research Interest: | , |
| Cell Type: | , , |
|
Preperation:
|
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
|
|
Formulation:
|
Phosphate-buffered aqueous solution, ph7.2.
|
|
References:
|
Maeda, M., Carpenito, C., Russell, R. C., Dasanjh, J., Veinotte, L. L., Ohta, H., … & Takei, F. (2005). Murine CD160, Ig-like receptor on NK cells and NKT cells, recognizes classical and nonclassical MHC class I and regulates NK cell activation. The Journal of Immunology, 175(7), 4426-4432. Anumanthan, A., Bensussan, A., Boumsell, L., Christ, A. D., Blumberg, R. S., Voss, S. D., … & Freeman, G. J. (1998). Cloning of BY55, a novel Ig superfamily member expressed on NK cells, CTL, and intestinal intraepithelial lymphocytes. The Journal of Immunology, 161(6), 2780-2790. Fons, P., Chabot, S., Cartwright, J. E., Lenfant, F., LFaqihi, F., Giustiniani, J., … & Le Bouteiller, P. (2006). Soluble HLA-G1 inhibits angiogenesis through an apoptotic pathway and by direct binding to CD160 receptor expressed by endothelial cells. Blood, 108(8), 2608-2615. |