Anti-Human/Mouse MCP-1 (CCL2) SAFIRE Purified
The 2H5 monoclonal antibody specifically reacts with mouse, rat, human MCP-1 (Monocyte Chemoattractant Protein-1), also known as CCL2 and MCAF (Monocyte Chemotactic and Activating Factor). MCP-1 is a C-C (beta) chemokine that regulates cytokine production in monocytes and the expression of adhesion molecules. The 2h5 antibody can neutralize the bioactivity of recombinant or natural MCP-1. AMG 232
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Clone
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2H5
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Format: |
SAFIRE Purified
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Applications
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FC, FA, Neutralization
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Reactivity
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Human, Mouse, Rat
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Isotype:
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Armenian Hamster IgG
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Preperation:
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The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
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Formulation:
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Phosphate-buffered aqueous solution, ph7.2.
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References:
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Luo, Y., Laning, J., Hayashi, M., Hancock, P. R., Rollins, B., & Dorf, M. E. (1994). Serologic analysis of the mouse beta chemokine JE/monocyte chemoattractant protein-1. The Journal of immunology, 153(8), 3708-3716. Bost, K. L., Bento, J. L., Petty, C. C., Schrum, L. W., Hudson, M. C., & Marriott, I. (2001). Monocyte chemoattractant protein-1 expression by osteoblasts following infection with Staphylococcus aureus or Salmonella.Journal of Interferon & Cytokine Research, 21(5), 297-304. Taal, M. W., Chertow, G. M., Rennke, H. G., Gurnani, A., Jiang, T., Shahsafaei, A., … & Mackenzie, H. S. (2001). Mechanisms underlying renoprotection during renin-angiotensin system blockade. American Journal of Physiology-Renal Physiology, 280(2), F343-F355. |