Product Name :
prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens]
Description:
prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens], (C26H41N9O9), a peptide with the sequence H2N-Ala-Thr-Gly-Gly-Tyr-Arg-OH, MW= 623.66. Prostate apoptosis response-4 (Par-4), is a human gene coding for a tumor-suppressor protein that induces apoptosis in cancer cells, but not in normal cells.The tumor suppressor PAR-4 represses and activates transcription. The protein encoded by this gene is a PAR-4-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of PAR-4. This protein is specifically upregulated during apoptosis of prostate cells1.The active domain of the Par-4 protein has been found to confer cancer resistance in transgenic mice without compromising normal viability or aging, and may have therapeutic significance2.
CAS:
Molecular Weight:
623.66
Formula:
C26H41N9O9
Chemical Name:
2-[2-(2-{2-[2-(2-aminopropanamido)-3-hydroxybutanamido]acetamido}acetamido)-3-(4-hydroxyphenyl)propanamido]-5-carbamimidamidopentanoic acid
Smiles :
CC(O)C(NC(=O)C(C)N)C(=O)NCC(=O)NCC(=O)NC(CC1C=CC(O)=CC=1)C(=O)NC(CCCNC(N)=N)C(O)=O
InChiKey:
YSIURJUKAKVWAQ-UHFFFAOYSA-N
InChi :
InChI=1S/C26H41N9O9/c1-13(27)22(40)35-21(14(2)36)24(42)32-11-19(38)31-12-20(39)33-18(10-15-5-7-16(37)8-6-15)23(41)34-17(25(43)44)4-3-9-30-26(28)29/h5-8,13-14,17-18,21,36-37H,3-4,9-12,27H2,1-2H3,(H,31,38)(H,32,42)(H,33,39)(H,34,41)(H,35,40)(H,43,44)(H4,28,29,30)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens], (C26H41N9O9), a peptide with the sequence H2N-Ala-Thr-Gly-Gly-Tyr-Arg-OH, MW= 623.66. Prostate apoptosis response-4 (Par-4), is a human gene coding for a tumor-suppressor protein that induces apoptosis in cancer cells, but not in normal cells.The tumor suppressor PAR-4 represses and activates transcription. The protein encoded by this gene is a PAR-4-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of PAR-4. This protein is specifically upregulated during apoptosis of prostate cells1.The active domain of the Par-4 protein has been found to confer cancer resistance in transgenic mice without compromising normal viability or aging, and may have therapeutic significance2.{{SQ109} MedChemExpress|{SQ109} Antibiotic|{SQ109} Biological Activity|{SQ109} In Vivo|{SQ109} supplier|{SQ109} Cancer} |Product information|Molecular Weight: 623.{{Iscalimab} web|{Iscalimab} TNF Receptor|{Iscalimab} Purity & Documentation|{Iscalimab} In stock|{Iscalimab} supplier|{Iscalimab} Autophagy} 66|Formula: C26H41N9O9|Chemical Name: 2-[2-(2-{2-[2-(2-aminopropanamido)-3-hydroxybutanamido]acetamido}acetamido)-3-(4-hydroxyphenyl)propanamido]-5-carbamimidamidopentanoic acid|Smiles: CC(O)C(NC(=O)C(C)N)C(=O)NCC(=O)NCC(=O)NC(CC1C=CC(O)=CC=1)C(=O)NC(CCCNC(N)=N)C(O)=O|InChiKey: YSIURJUKAKVWAQ-UHFFFAOYSA-N|InChi: InChI=1S/C26H41N9O9/c1-13(27)22(40)35-21(14(2)36)24(42)32-11-19(38)31-12-20(39)33-18(10-15-5-7-16(37)8-6-15)23(41)34-17(25(43)44)4-3-9-30-26(28)29/h5-8,13-14,17-18,21,36-37H,3-4,9-12,27H2,1-2H3,(H,31,38)(H,32,42)(H,33,39)(H,34,41)(H,35,40)(H,43,44)(H4,28,29,30)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:23290930 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|