Anti-Human IFN gamma PE-Cyanine7
The 4S.B3 is a neutralizing antibody that binds with the human Interferon-gamma (IFN-γ) protein, a 15 -17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties. When secreted by natural killer cells and by natural killer T lymphocytes, it regulates the immune response and supports adaptive immunity when produced by Th1 or CD8+ T lymphocytes. IFN-γ plays an important role in the activation, the growth, and the differentiation of the macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-α, to inhibit proliferation of normal and transformed cells. IFN- γ is the primary cytokine that defines Th-1 cells. The biological activity of IFN-γ is not affected by glycosylation. RG7388
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Clone
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4S.B3
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Format: |
PE-Cyanine7
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Applications
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FC, Neutralization,
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Reactivity
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Human
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Isotype:
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Mouse IgG1, kappa
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| Research Interest: |
, , Cytokines & Growth Factors |
| Cell Type: |
Th1 cells, , |
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Preperation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Meager, A. (1987). Antibodies against interferons: Characterization of interferons and immunoassays. Lymphockies and Interferons. A Practical Approach. Clemens, MJ, AG Morris, and AJH Gearing, eds. IRL Press Ltd. Oxford, 105.
Meager, A., Parti, S., Barwick, S., Spragg, J., & Ohagan, K. (1984). Detection of hybridomas secreting monoclonal antibodies to human gamma interferon using a rapid screening technique and specificity of certain monoclonal antibodies to gamma interferon. Journal of interferon research, 4(4), 619-625.
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MED: 19038281
Anti-Human IFN gamma PE-Cyanine7
The 4S.B3 is a neutralizing antibody that binds with the human Interferon-gamma (IFN-γ) protein, a 15 -17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties. When secreted by natural killer cells and by natural killer T lymphocytes, it regulates the immune response and supports adaptive immunity when produced by Th1 or CD8+ T lymphocytes. IFN-γ plays an important role in the activation, the growth, and the differentiation of the macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-α, to inhibit proliferation of normal and transformed cells. IFN- γ is the primary cytokine that defines Th-1 cells. The biological activity of IFN-γ is not affected by glycosylation. NVP-TNKS657
|
Clone
|
4S.B3
|
|
Format: |
PE-Cyanine7
|
|
Applications
|
FC, Neutralization,
|
|
Reactivity
|
Human
|
|
Isotype:
|
Mouse IgG1, kappa
|
| Research Interest: |
, , Cytokines & Growth Factors |
| Cell Type: |
Th1 cells, , |
|
Preperation:
|
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
|
|
Formulation:
|
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
|
|
References:
|
Meager, A. (1987). Antibodies against interferons: Characterization of interferons and immunoassays. Lymphockies and Interferons. A Practical Approach. Clemens, MJ, AG Morris, and AJH Gearing, eds. IRL Press Ltd. Oxford, 105.
Meager, A., Parti, S., Barwick, S., Spragg, J., & Ohagan, K. (1984). Detection of hybridomas secreting monoclonal antibodies to human gamma interferon using a rapid screening technique and specificity of certain monoclonal antibodies to gamma interferon. Journal of interferon research, 4(4), 619-625.
|
MED: 19050248
Anti-Human IFN gamma PE-Cyanine7
The 4S.B3 is a neutralizing antibody that binds with the human Interferon-gamma (IFN-γ) protein, a 15 -17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties. When secreted by natural killer cells and by natural killer T lymphocytes, it regulates the immune response and supports adaptive immunity when produced by Th1 or CD8+ T lymphocytes. IFN-γ plays an important role in the activation, the growth, and the differentiation of the macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-α, to inhibit proliferation of normal and transformed cells. IFN- γ is the primary cytokine that defines Th-1 cells. The biological activity of IFN-γ is not affected by glycosylation. NVP-TNKS657
|
Clone
|
4S.B3
|
|
Format: |
PE-Cyanine7
|
|
Applications
|
FC, Neutralization,
|
|
Reactivity
|
Human
|
|
Isotype:
|
Mouse IgG1, kappa
|
| Research Interest: |
, , Cytokines & Growth Factors |
| Cell Type: |
Th1 cells, , |
|
Preperation:
|
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
|
|
Formulation:
|
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
|
|
References:
|
Meager, A. (1987). Antibodies against interferons: Characterization of interferons and immunoassays. Lymphockies and Interferons. A Practical Approach. Clemens, MJ, AG Morris, and AJH Gearing, eds. IRL Press Ltd. Oxford, 105.
Meager, A., Parti, S., Barwick, S., Spragg, J., & Ohagan, K. (1984). Detection of hybridomas secreting monoclonal antibodies to human gamma interferon using a rapid screening technique and specificity of certain monoclonal antibodies to gamma interferon. Journal of interferon research, 4(4), 619-625.
|
MED: 19050248