Product Name :
Candesartan, 98%
Synonym:
IUPAC Name :
CAS NO.:
139481-59-7
Molecular Weight :
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Smiles:
Description:
Candesartan is a selective AT1 (angiotensin II receptor 1) antagonist.Lycorine Antagonism of angiotensin receptors inhibits vasoconstriction and the production of aldosterone, leading to a decrease in water and sodium concentration in blood plasma.Sphingosine-1-phosphate Exhibits antihypertensive effects in animal models.PMID:23626759 Used in treatment of congestive heart failure, as antihypertensive. Candesartan does not affect cell viability or proliferation but increases the expression of VEGF and interleukin-8 in the cultured medium of KU-19-19 cells. Candesartan (0.1 nM) could reduce the maximal contractile response to angiostensin II by approximately 50%.