Name : IL-6, Human
Product Concentration :
Background :
Interleukin-6 (IL-6), also known as BSF-2, CDF and IFNB2, is a pleiotropic cytokine that participates in both pro-inflammatory and anti-inflammatory responses. It is produced mainly by T cells, macrophages, monocytes, endothelial cells and muscle cells. IL-6 binds to IL-6 receptor (IL-6R) to trigger the association of IL-6R with gp130, inducing signal transduction through JAKs and STATs. The biological functions of IL-6 are diverse. It stimulates B cell differentiation and antibody production, myeloma and plasmacytoma growth, and nerve cell differentiation. It also acts as a myokine, produced by muscle cells in response to muscle contraction and released into the blood stream to help break down fats and improve insulin resistance.
Biological Activity :
IL-6, Human (Cat. No. Z03034) stimulates cell proliferation of 7TD1 cells. The ED50 for this effect is less than 0.1ng/mL. 2 μg of IL-6, Human (Cat. No. Z03034) was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie Blue staining IL-6, Human Interleukin-6 (IL-6), also known as BSF-2, CDF and IFNB2, is a pleiotropic cytokine that participates in both pro-inflammatory and anti-inflammatory responses. It is produced mainly by T cells, macrophages, monocytes, endothelial cells and muscle cells. IL-6 binds to IL-6 receptor (IL-6R) to trigger the association of IL-6R with gp130, inducing signal transduction through JAKs and STATs. The biological functions of IL-6 are diverse. It stimulates B cell differentiation and antibody production, myeloma and plasmacytoma growth, and nerve cell differentiation. It also acts as a myokine, produced by muscle cells in response to muscle contraction and released into the blood stream to help break down fats and improve insulin resistance. .hide { display: none!important; } .product_table_cart_div{ width: 100%; } .product_table_cart_div .unit{ display: block; font-weight: bold; min-width: 120px; text-align: left; width: 100px; } .form-control{ width: 45px; height: 30px; line-height: 30px; display: inline; padding: 0px 0px 0px 5px; } .product_table_cart_div .size-box{ padding: 4px 5px; border: 1px solid #cccccc; text-align: center; margin-right: 10px; } .product_table_cart_div span{ color: black !important; } .product_table_cart_div .price{ font-weight: 600; font-style: normal; color: #1D73DD; font-size: 30px; text-align: left; color: #F41D27 !important; } .product_table_cart_div .price-td{ padding-bottom:50px !important; } .btn-add-to-cart .button-face{ height: 40px; font-size: 16px; } .size-list div{ display: inline-block; } .ask-us{ color: #1D73DD; margin: 0 10px; } .btn-add-to-cart{ width: 180px; }
expression system :
E. coli
Tag :
Expressed with an N-terminal Met. IL-6 (Pro29-Met212)Accession # Q75MH2
Protein Accession No. :
Q75MH2
Synonyms :
IL6; 26 kDa protein; IFN-β2; IFN-b2; B cell differentiation factor; BCDF; BSF-2; HPGF; HSF; MGI-2
Molecular Weight :
~20.9 kDa, on SDS-PAGE under reducing conditions.
Purity :
> 95% as analyzed by SDS-PAGE
Product Concentration :
Lyophilized after extensive dialysis against PBS.
Storage and Stability :
Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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