Al[11,12]. three. ResultThe bioactive compounds present in the ethanolic extract of leaf of E. serratus have been identified by GC-MS evaluation (Figure 1).RT: 0.00-46.four.2 4.0 three.8 3.6 3.4 three.2 three.0 2.8 two.six 2.4 2.2 two.0 1.eight 1.6 1.4 1.2 1.0 0.8 0.6 0.4 0.two 0.T he identity of your components within the extract wasNL:RT: retention time.p-Menthane-1-thiol 1-Benzylthio-4-methyl-1,3-pentadiene 1-Octadecanol Citronellyl isobutyrate Docosanoic acid, 1,two,3-propanetriyl ester 2-Octyldodecan-1-ol Ricinoleic acid Dotriacontane Hexadecanoic acid, methyl ester 1-Hexadecene Pent-4-enal 9-Nitro-1-nonene 1-(Chloromethyl)-3-methylene-1-cyclobutanol Cyclohexane, ethyl5,6-Epoxy-6-methyl-1,9-decadien-4-one 2-Methylsulfonyl-3,3-diethyloxirane 8-Ethenyloxocan-2-one 1-Dotriacontanol NOD-like Receptor (NLR) web farnesol N-Benzyl-N-(1-phenylethylidene)amine1-(Pent-1-enyl)cyclopropanolC18H38OC69H98O132 112 180 178 154 466 222C7H14O3S6.73ETIC MS EM-4. DiscussionAmong the identified phytochemicals, the fatty acid esters namely, docosanoic acid, 1,two,3-propanetriyl ester, hexadecanoic acid methyl ester have the property of antioxidant, hypocholesterolemic, nematicide, pesticide, flavouring agent, lubricant and anti-androgenic activities. The biological activities listed are according to Dr. Duke’s phytochemical and ethanobotanical databases by Dr. Jim Duke of the Agricultural Analysis Service/USDA. Analogous for the present study, hexadecanoic acid methyl ester was identified inside the methanol extract of Spirulina platensis[13]. The ethanolic extract of Mussaenda frondosa was subjected to GC-MS analysis and 20 chemical constituents namely ( – ) -quinic acid, 4 – (( 1 e ) – 3 -hydroxy- 1 -propenyl ) – two methoxyphenol, naphthalene,decahydro- 2 -methoxy, 1 , 2, 3-benzenetriol, hexadecanoic acid ethyl ester, linoleicRelative abundance17.26.68 3.44 3.61 3.78 13.67 3.73 30.95 four.16 23.21 9.99 four.45 35.00 17.95 4.79 29.00 36.91 24.07 13.19 17.67 five.72 34.91 19.38 six.03 0 5 ten 15 20 25 3022.41.38 41.52 41.T hirty compounds were detected inside the ethanolic extract of E. serratus leaf. The active principles with their retention time, molecular formula, molecular weight and concentration ( ) in the ethanol extracts of leaf of E. serratusFigure 1. GC-MS GLP Receptor Agonist custom synthesis chromatogram of ethanolic extract on the leaf of E. serratus.Geetha DH et al./Asian Pac J Trop Biomed 2013; 3(12): 985-acid ethyl ester, oleic acid, etc. were identified[14]. The compounds farnesol and citronellyl isobutyrate are present within the ethanolic leaf extract of E. serratus. The compound farnesol is an acyclic sesquiterpene alcohol, and it has been recommended to function as a chemopreservative and antitumor agent[15]. It is also utilised as a deodorant in cosmetic merchandise due to its anti-bacterial activity[16]. T he anti-fungal activity of farnesol has also been reported[17]. Citronellyl isobutyrate is definitely an ester of propanoic acid which is extensively utilised as flavoring agent and is recognized to possess insect repellent and antimicrobial properties[18-20]. Our systematic investigation reveals the prospective of E. serratus leaves as a great source of bioactive compounds for instance fatty acid esters, alcohols, hydrocarbons, aldehydes, alkenes, fatty acids and amides that justify the usage of this plant for its different ailments by standard practitioners. Additional investigation interest inside the study of these active bio compounds might yield nature friendly powerful antioxidant, anti-microbial, anti-inflammatory agents and analgesic agents. Conflict of interest statement We declare that we have no conflict of in.