Product Name :
6H05
Description:
6H05 TFA is a selective and allosteric inhibitor of oncogenic K-Ras(G12C) .
CAS:
1469338-01-9
Molecular Weight:
476.12
Formula:
C20H30ClN3O2S3
Chemical Name:
1-2-[(4-chlorophenyl)sulfanyl]acetyl-N-(2-[2-(dimethylamino)ethyl]disulfanylethyl)piperidine-4-carboxamide
Smiles :
CN(C)CCSSCCNC(=O)C1CCN(CC1)C(=O)CSC1C=CC(Cl)=CC=1
InChiKey:
WEEYMZOUPNIHLG-UHFFFAOYSA-N
InChi :
InChI=1S/C20H30ClN3O2S3/c1-23(2)12-14-29-28-13-9-22-20(26)16-7-10-24(11-8-16)19(25)15-27-18-5-3-17(21)4-6-18/h3-6,16H,7-15H2,1-2H3,(H,22,26)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Entacapone Autophagy
Shelf Life:
≥12 months if stored properly.Nirogacestat custom synthesis
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
6H05 TFA is a selective and allosteric inhibitor of oncogenic K-Ras(G12C) .|Product information|CAS Number: 1469338-01-9|Molecular Weight: 476.12|Formula: C20H30ClN3O2S3|Chemical Name: 1-2-[(4-chlorophenyl)sulfanyl]acetyl-N-(2-[2-(dimethylamino)ethyl]disulfanylethyl)piperidine-4-carboxamide|Smiles: CN(C)CCSSCCNC(=O)C1CCN(CC1)C(=O)CSC1C=CC(Cl)=CC=1|InChiKey: WEEYMZOUPNIHLG-UHFFFAOYSA-N|InChi: InChI=1S/C20H30ClN3O2S3/c1-23(2)12-14-29-28-13-9-22-20(26)16-7-10-24(11-8-16)19(25)15-27-18-5-3-17(21)4-6-18/h3-6,16H,7-15H2,1-2H3,(H,22,26)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:31869177 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Ostrem J M , Peters U , Sos M L , et al. K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions[J]. Nature, 2013, 503(7477):548-551.Lu S , Li S , Zhang J . Harnessing Allostery: A Novel Approach to Drug Discovery[J]. Medicinal Research Reviews, 2014, 34(6):1242-1285.Products are for research use only. Not for human use.|