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Procollagen type I (CT) (human) monoclonal antibody (8)
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Type I collagen is present in connective tissue and bone where it makes up about 90% of the organic matrix.{{204005-46-9} web|{204005-46-9} Purity & Documentation|{204005-46-9} Data Sheet|{204005-46-9} supplier} Type I collagen is produced from type-I procollagen by the proteolytic cleavage of N- and C-telopeptides, which are released into the circulation.{{254435-95-5} medchemexpress|{254435-95-5} Biological Activity|{254435-95-5} In stock|{254435-95-5} custom synthesis} The propeptides can be measured in serum as markers of the production of type-I collagen. Elevated values of these propeptides are found in serum from patients with various metabolic or malignant bone diseases.PMID:29763121 Procollagen type I C-terminal propeptide (PICP) has a molecular mass of approximately 100kDa. Its normal concentration in serum depends on age and sex.
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| Alternative Name Type I collagen, Procollagen type I C-terminal propeptide, PICP | Application ELISA, IP | Clone 8 | Formulation Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. | GenBank ID 1277 | Host Mouse | Immunogen Purified human PICP from second trimester amniotic fluid. | Isotype IgG1κ | Source From culture supernatant. | Species Reactivity Human | Specificity Specific for for native PICP from amniotic fluid. | UniProt ID P02452 | Unit of Measure (UM) mg, µg