Product Name :
PKI (5-24)
Sequence:
Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-His-Asp
Purity:
≥95% (HPLC)
Molecular Weight:
2222.7
Solubility :
Soluble in water.
Appearance:
White to off-white solid
Use/Stability :
As indicated on product label or CoA when stored as recommended. Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
Description:
PKA inhibitor Sequence is from the heat-stable skeletal muscle inhibitor protein of PKA.{{474-62-4} MedChemExpress|{474-62-4} Biological Activity|{474-62-4} Formula|{474-62-4} supplier} Peptide binds to the catalytic subunit of PKA and displaces the regulatory subunit.{{231277-92-2} medchemexpress|{231277-92-2} Technical Information|{231277-92-2} References|{231277-92-2} custom synthesis} Mimics protein substrate by binding to the catalytic site via the Arg-cluster basic residues.PMID:30794481 Ki =2.3 nM for PKA.
CAS :
99534-03-9
Solubility:
Soluble in water.
Formula:
C94H148N32O31
Additional Information :
| Alternative Name cAMP-dependent protein kinase inhibitor (5-24) | Appearance White to off-white solid | CAS 99534-03-9 | Formula C94H148N32O31 | Formulation Lyophilized. | MW 2222.7 | Purity ≥95% (HPLC) | Sequence Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-His-Asp | Solubility Soluble in water. | Source Synthetic.