Product Name :
Polaprezinc

Description:
Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-oxidant, anti-ulcer and anti-inflammatory activities.

CAS:
107667-60-7

Molecular Weight:
290.63

Formula:
C9H13N4O3Zn

Chemical Name:
(3-aminopropanoyl)[(1S)-1-carboxy-2-(1H-imidazol-5-yl)ethyl]azanide zinc

Smiles :
[Zn].NCCC(=O)[N-][C@@H](CC1=CN=CN1)C(O)=O

InChiKey:
GFWBKUDRXMQSFD-FJXQXJEOSA-M

InChi :
InChI=1S/C9H14N4O3.Zn/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6;/h4-5,7H,1-3,10H2,(H3,11,12,13,14,15,16);/p-1/t7-;/m0.{{Troglitazone} site|{Troglitazone} Autophagy|{Troglitazone} Biological Activity|{Troglitazone} Data Sheet|{Troglitazone} manufacturer|{Troglitazone} Autophagy} /s1

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Glycerol-d5} medchemexpress|{Glycerol-d5} Metabolic Enzyme/Protease|{Glycerol-d5} Technical Information|{Glycerol-d5} In Vivo|{Glycerol-d5} custom synthesis|{Glycerol-d5} Autophagy}

Shelf Life:
≥12 months if stored properly.PMID:32491315

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-oxidant, anti-ulcer and anti-inflammatory activities.|Product information|CAS Number: 107667-60-7|Molecular Weight: 290.63|Formula: C9H13N4O3Zn|Chemical Name: (3-aminopropanoyl)[(1S)-1-carboxy-2-(1H-imidazol-5-yl)ethyl]azanide zinc|Smiles: [Zn].NCCC(=O)[N-][C@@H](CC1=CN=CN1)C(O)=O|InChiKey: GFWBKUDRXMQSFD-FJXQXJEOSA-M|InChi: InChI=1S/C9H14N4O3.Zn/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6;/h4-5,7H,1-3,10H2,(H3,11,12,13,14,15,16);/p-1/t7-;/m0./s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Polaprezinc (PZ) is an antiulcer drug and a chelating compound consisting of a zinc ion, L-carnosine, a β-alanine dipeptide and L-histidine. Polaprezinc exerts antioxidant effects and scavenges free radicals. The efficacy of Polaprezinc is reported for acute radiation proctitis in an animal model and demonstrates that Polaprezinc has an anti-inflammatory effect following exposure to radiation.|Products are for research use only. Not for human use.|

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