Product Name :
LPS from Salmonella minnesota R345 (Rb) (TLRGRADE®) (Ready-to-Use)
Sequence:
Purity:
Absence of detectable protein or DNA contaminants with agonistic TLR activity.
Molecular Weight:
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Appearance:
Use/Stability :
As indicated on product label or CoA when stored as recommended.{{391210-10-9} site|{391210-10-9} Protocol|{391210-10-9} Formula|{391210-10-9} supplier} Stable for at least 1 year after receipt when stored at +4°C.
Description:
TLR4 activator
CAS :
Solubility:
Formula:
Additional Information :
| Activity Strong activator of Toll-like receptor 4 (TLR4).{{9027-96-7} site|{9027-96-7} Purity & Documentation|{9027-96-7} In Vivo|{9027-96-7} supplier} Does not activate TLR2 or other TLRs as determined with splenocytes and macrophages from TLR4 deficient mice.PMID:25905170 No further re-extraction required.Smooth (S)-form LPS are commonly the preferred choice for whole animal studies, whereas Rough (R)-form LPS are primarily used in cellular in vitro activation studies. | Alternative Name Lipopolysaccharide from Salmonella minnesota R345 (Rb) | Couple Target TLR, TLR4 | Couple Type Activator, Ligand | Formulation Liquid. Sterile, ready-to-use solution in pyrogen-free double distilled water. | Purity Absence of detectable protein or DNA contaminants with agonistic TLR activity. | Source Rough (R)-form LPS, isolated and purified from Salmonella minnesota R345 (Rb mutant) by a modification of the PCP extraction method, converted to the uniform sodium salt form and dissolved in sterile pyrogen-free double distilled water. | Unit of Measure (UM) ml