Product Name :
Bidisomide
Description:
Bidisomide (SC40230) is a class I antiarrhythmic agent.
CAS:
116078-65-0
Molecular Weight:
407.98
Formula:
C22H34ClN3O2
Chemical Name:
2-(2-chlorophenyl)-4-(piperidin-1-yl)-2-{2-[N-(propan-2-yl)acetamido]ethyl}butanamide
Smiles :
CC(=O)N(CCC(CCN1CCCCC1)(C1=CC=CC=C1Cl)C(N)=O)C(C)C
InChiKey:
GTEPPJFJSNSNIH-UHFFFAOYSA-N
InChi :
InChI=1S/C22H34ClN3O2/c1-17(2)26(18(3)27)16-12-22(21(24)28,19-9-5-6-10-20(19)23)11-15-25-13-7-4-8-14-25/h5-6,9-10,17H,4,7-8,11-16H2,1-3H3,(H2,24,28)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Amrubicin} web|{Amrubicin} Cell Cycle/DNA Damage|{Amrubicin} Technical Information|{Amrubicin} Formula|{Amrubicin} supplier|{Amrubicin} Cancer}
Shelf Life:
≥12 months if stored properly.{{Nociceptin} MedChemExpress|{Nociceptin} GPCR/G Protein|{Nociceptin} Biological Activity|{Nociceptin} Formula|{Nociceptin} manufacturer|{Nociceptin} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Bidisomide (SC40230) is a class I antiarrhythmic agent.|Product information|CAS Number: 116078-65-0|Molecular Weight: 407.98|Formula: C22H34ClN3O2|Chemical Name: 2-(2-chlorophenyl)-4-(piperidin-1-yl)-2-{2-[N-(propan-2-yl)acetamido]ethyl}butanamide|Smiles: CC(=O)N(CCC(CCN1CCCCC1)(C1=CC=CC=C1Cl)C(N)=O)C(C)C|InChiKey: GTEPPJFJSNSNIH-UHFFFAOYSA-N|InChi: InChI=1S/C22H34ClN3O2/c1-17(2)26(18(3)27)16-12-22(21(24)28,19-9-5-6-10-20(19)23)11-15-25-13-7-4-8-14-25/h5-6,9-10,17H,4,7-8,11-16H2,1-3H3,(H2,24,28)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32985252 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|The antiarrhythmic effects of Bidisomide, a new class I antiarrhythmic drug is investigated in early-phase ventricular arrhythmias induced by coronary artery occlusion and reperfusion in anesthetized rats. Bidisomide (5 mg/kg) reduces the number of premature ventricular complexes and the incidence of ventricular tachycardia and ventricular fibrillation similarly to Mexiletine (MXT) and Disopyramide (DSP) in rats with ventricular arrhythmias induced by coronary artery occlusion. In rats with ventricular arrhythmias induced by coronary artery reperfusion following a 5 min coronary occlusion, the antiarrhythmic effects of 5 mg/kg of Bidisomide are similar to those of the same doses of MXT and DSP. All three drugs significantly slow the heart rate.|Products are for research use only. Not for human use.|