Product Name :
SR8278

Description:
SR8278 is a competitive nuclear heme receptor REV-ERB synthetic antagonist. SR8278 inhibits the REV-ERBα transcriptional repression activity with an EC50 of 0.47μM. SR8278 is used to regulate the metabolism in organisms and study biological rhythm.

CAS:
1254944-66-5

Molecular Weight:
361.48

Formula:
C18H19NO3S2

Chemical Name:
ethyl 2-[5-(methylsulfanyl)thiophene-2-carbonyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylate

Smiles :
CSC1=CC=C(S1)C(=O)N1CC2=CC=CC=C2CC1C(=O)OCC

InChiKey:
UIEBLUZPSFAFOC-UHFFFAOYSA-N

InChi :
InChI=1S/C18H19NO3S2/c1-3-22-18(21)14-10-12-6-4-5-7-13(12)11-19(14)17(20)15-8-9-16(23-2)24-15/h4-9,14H,3,10-11H2,1-2H3

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
SR8278 is a competitive nuclear heme receptor REV-ERB synthetic antagonist. SR8278 inhibits the REV-ERBα transcriptional repression activity with an EC50 of 0.47μM. SR8278 is used to regulate the metabolism in organisms and study biological rhythm.|Product information|CAS Number: 1254944-66-5|Molecular Weight: 361.48|Formula: C18H19NO3S2|Chemical Name: ethyl 2-[5-(methylsulfanyl)thiophene-2-carbonyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylate|Smiles: CSC1=CC=C(S1)C(=O)N1CC2=CC=CC=C2CC1C(=O)OCC|InChiKey: UIEBLUZPSFAFOC-UHFFFAOYSA-N|InChi: InChI=1S/C18H19NO3S2/c1-3-22-18(21)14-10-12-6-4-5-7-13(12)11-19(14)17(20)15-8-9-16(23-2)24-15/h4-9,14H,3,10-11H2,1-2H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (276.{{Danuglipron} web|{Danuglipron} GPCR/G Protein|{Danuglipron} Purity & Documentation|{Danuglipron} Data Sheet|{Danuglipron} custom synthesis|{Danuglipron} Autophagy} 64 mM; Need ultrasonic).{{Domvanalimab} medchemexpress|{Domvanalimab} Technical Information|{Domvanalimab} Description|{Domvanalimab} manufacturer|{Domvanalimab} Epigenetic Reader Domain} |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32703026 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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