Product Name :
GDC-0084
CAS No.:
1382979-44-3
Purity :
> 98%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
CC1(C)OCC[N]2C3=C(N=C12)C(=NC(=N3)C4=CN=C(N)N=C4)N5CCOCC5
Product Description :
GDC-0084 is a brain penetrant inhibitor of PI3K and mTOR with Kiapp values of 2 nM, 46 nM, 3 nM, 10 nM and 70 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR.{{2055200-88-7} MedChemExpress|{2055200-88-7} Technical Information|{2055200-88-7} References|{2055200-88-7} manufacturer}
Formula:
C18H22N8O2
Molecular Weight :
382.{{97682-44-5} site|{97682-44-5} Technical Information|{97682-44-5} References|{97682-44-5} custom synthesis} 42
Synonyms:
Additional Information:
|CAS No.PMID:26247092 1382979-44-3 ; |Formula C18H22N8O2 ; |Molecular Weight 382.42 ; |SMILES CC1(C)OCC[N]2C3=C(N=C12)C(=NC(=N3)C4=CN=C(N)N=C4)N5CCOCC5 ; |Target mTOR ; |Product Description GDC-0084 is a brain penetrant inhibitor of PI3K and mTOR with Kiapp values of 2 nM, 46 nM, 3 nM, 10 nM and 70 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR. ; |Purity > 98% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO