Product Name :
Integrin Antagonists 27
Description:
Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist with binding affinity of 18 nM, as s novel anticancer agent. Target: Integrinin vitro: Integrin Antagonists 27 is treated with a panel of cancer cell-lines (breast cancer cell line MDA-MB-435, breast cancer cell lines MCF-7, mouse fibroblast NIH3T3, ovarian cancer cell line HEY, lung cancer cell line NCI-H1975) with all IC50 of >20 uM.
CAS:
593274-97-6
Molecular Weight:
444.44
Formula:
C24H20N4O5
Chemical Name:
3-(2-{[(4Z)-1-{[(4-methylphenyl)carbamoyl]methyl}-2,5-dioxoimidazolidin-4-ylidene]methyl}-1H-pyrrol-1-yl)benzoic acid
Smiles :
CC1C=CC(=CC=1)NC(=O)CN1C(=O)N/C(=C\C2=CC=CN2C2C=CC=C(C=2)C(O)=O)/C1=O
InChiKey:
BJCKKLXERBMNHP-MOSHPQCFSA-N
InChi :
InChI=1S/C24H20N4O5/c1-15-7-9-17(10-8-15)25-21(29)14-28-22(30)20(26-24(28)33)13-19-6-3-11-27(19)18-5-2-4-16(12-18)23(31)32/h2-13H,14H2,1H3,(H,25,29)(H,26,33)(H,31,32)/b20-13-
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist with binding affinity of 18 nM, as s novel anticancer agent. Target: Integrinin vitro: Integrin Antagonists 27 is treated with a panel of cancer cell-lines (breast cancer cell line MDA-MB-435, breast cancer cell lines MCF-7, mouse fibroblast NIH3T3, ovarian cancer cell line HEY, lung cancer cell line NCI-H1975) with all IC50 of >20 uM.{{DSPC} site|{DSPC} Liposome|{DSPC} Activator|{DSPC} Protocol|{DSPC} Formula|{DSPC} manufacturer} |Product information|CAS Number: 593274-97-6|Molecular Weight: 444.{{Selinexor} MedChemExpress|{Selinexor} CRM1|{Selinexor} Protocol|{Selinexor} In stock|{Selinexor} manufacturer|{Selinexor} Autophagy} 44|Formula: C24H20N4O5|Chemical Name: 3-(2-{[(4Z)-1-{[(4-methylphenyl)carbamoyl]methyl}-2,5-dioxoimidazolidin-4-ylidene]methyl}-1H-pyrrol-1-yl)benzoic acid|Smiles: CC1C=CC(=CC=1)NC(=O)CN1C(=O)N/C(=C\C2=CC=CN2C2C=CC=C(C=2)C(O)=O)/C1=O|InChiKey: BJCKKLXERBMNHP-MOSHPQCFSA-N|InChi: InChI=1S/C24H20N4O5/c1-15-7-9-17(10-8-15)25-21(29)14-28-22(30)20(26-24(28)33)13-19-6-3-11-27(19)18-5-2-4-16(12-18)23(31)32/h2-13H,14H2,1H3,(H,25,29)(H,26,33)(H,31,32)/b20-13-|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : ≥ 100 mg/mL (225.PMID:23789847 00 mM).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|