Product Name :
Taribavirin hydrochloride
Description:
Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin hydrochloride is a Ribavirin prodrug, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia.
CAS:
40372-00-7
Molecular Weight:
279.68
Formula:
C8H14ClN5O4
Chemical Name:
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboximidamide hydrochloride
Smiles :
Cl.NC(=N)C1N=CN(N=1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
InChiKey:
PIGYMBULXKLTCJ-UHSSARMYSA-N
InChi :
InChI=1S/C8H13N5O4.ClH/c9-6(10)7-11-2-13(12-7)8-5(16)4(15)3(1-14)17-8;/h2-5,8,14-16H,1H2,(H3,9,10);1H/t3-,4-,5-,8-;/m1./s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Nicotinamide riboside} web|{Nicotinamide riboside} Endogenous Metabolite|{Nicotinamide riboside} Protocol|{Nicotinamide riboside} In stock|{Nicotinamide riboside} manufacturer|{Nicotinamide riboside} Epigenetics}
Shelf Life:
≥12 months if stored properly.{{FMK} site|{FMK} Ribosomal S6 Kinase (RSK)|{FMK} Protocol|{FMK} References|{FMK} custom synthesis|{FMK} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24367939
Additional information:
Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin hydrochloride is a Ribavirin prodrug, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia.|Product information|CAS Number: 40372-00-7|Molecular Weight: 279.68|Formula: C8H14ClN5O4|Chemical Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboximidamide hydrochloride|Smiles: Cl.NC(=N)C1N=CN(N=1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O|InChiKey: PIGYMBULXKLTCJ-UHSSARMYSA-N|InChi: InChI=1S/C8H13N5O4.ClH/c9-6(10)7-11-2-13(12-7)8-5(16)4(15)3(1-14)17-8;/h2-5,8,14-16H,1H2,(H3,9,10);1H/t3-,4-,5-,8-;/m1./s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Taribavirin hydrochloride (0-2 μM; 24 hours) significantly induces MCF-7 cell death, recording half inhibitory effect (IC50) of 0.756 μM in MCF-7 cells.|Products are for research use only. Not for human use.|