Product Name :
c-Fms-IN-9
Description:
c-Fms-IN-9 is a c-FMS inhibitor extracted from patent WO2014145023A1, Compound Example 7. c-Fms-IN-9 inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT with IC50s of <0.01 μM and 0.1-1 μM, respectively.
CAS:
1628574-50-4
Molecular Weight:
405.45
Formula:
C21H23N7O2
Chemical Name:
3-tert-butyl-1-(6-methyl-5-{[2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yl]oxy}pyridin-2-yl)-4,5-dihydro-1H-1,2,4-triazol-5-one
Smiles :
CN1C=C(C=N1)C1=CC(=CC=N1)OC1=CC=C(N=C1C)N1N=C(NC1=O)C(C)(C)C
InChiKey:
DKZTVZFTPXVEJW-UHFFFAOYSA-N
InChi :
InChI=1S/C21H23N7O2/c1-13-17(30-15-8-9-22-16(10-15)14-11-23-27(5)12-14)6-7-18(24-13)28-20(29)25-19(26-28)21(2,3)4/h6-12H,1-5H3,(H,25,26,29)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Hemocyanin} medchemexpress|{Hemocyanin} Endogenous Metabolite|{Hemocyanin} Purity & Documentation|{Hemocyanin} Formula|{Hemocyanin} custom synthesis|{Hemocyanin} Autophagy}
Shelf Life:
≥12 months if stored properly.{{Daclatasvir} MedChemExpress|{Daclatasvir} HCV|{Daclatasvir} Biological Activity|{Daclatasvir} Description|{Daclatasvir} manufacturer|{Daclatasvir} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23522542
Additional information:
c-Fms-IN-9 is a c-FMS inhibitor extracted from patent WO2014145023A1, Compound Example 7. c-Fms-IN-9 inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT with IC50s of Product information|CAS Number: 1628574-50-4|Molecular Weight: 405.45|Formula: C21H23N7O2|Chemical Name: 3-tert-butyl-1-(6-methyl-5-{[2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yl]oxy}pyridin-2-yl)-4,5-dihydro-1H-1,2,4-triazol-5-one|Smiles: CN1C=C(C=N1)C1=CC(=CC=N1)OC1=CC=C(N=C1C)N1N=C(NC1=O)C(C)(C)C|InChiKey: DKZTVZFTPXVEJW-UHFFFAOYSA-N|InChi: InChI=1S/C21H23N7O2/c1-13-17(30-15-8-9-22-16(10-15)14-11-23-27(5)12-14)6-7-18(24-13)28-20(29)25-19(26-28)21(2,3)4/h6-12H,1-5H3,(H,25,26,29)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|c-Fms-IN-9 inhibits M-NFS-60, THP-1 and osteoclast cells proliferation with IC50s of 0.01-0.1 μM.|Products are for research use only. Not for human use.|