Product Name :
pan-HER-IN-1
Description:
pan-HER-IN-1 (Compound C5) is an irreversible, orally active pan-HER inhibitor with IC5o values of 0.38, 1.6, 2.2 and 3.5 nM against EGFR. HER4. EGFR T790M/L858R and HER2, respectively. pan-HER-IN-1 induces apoptosis and shows antitumor activities !!).
CAS:
1639040-94-0
Molecular Weight:
408.25
Formula:
C19H14BrN5O
Chemical Name:
Smiles :
C=CC(=O)NC1=CC2=C(NC3C=C4C(Br)=CNC4=CC=3)N=CN=C2C=C1
InChiKey:
ATUXFPJRTSKHFB-UHFFFAOYSA-N
InChi :
InChI=1S/C19H14BrN5O/c1-2-18(26)24-11-3-6-17-14(8-11)19(23-10-22-17)25-12-4-5-16-13(7-12)15(20)9-21-16/h2-10,21H,1H2,(H,24,26)(H,22,23,25)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Domperidone monomaleate} site|{Domperidone monomaleate} Dopamine Receptor|{Domperidone monomaleate} Technical Information|{Domperidone monomaleate} In Vivo|{Domperidone monomaleate} custom synthesis|{Domperidone monomaleate} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
pan-HER-IN-1 (Compound C5) is an irreversible, orally active pan-HER inhibitor with IC5o values of 0.38, 1.6, 2.2 and 3.5 nM against EGFR.{{Anti-Mouse IFNAR1 Antibody (MAR1-5A3)} site|{Anti-Mouse IFNAR1 Antibody (MAR1-5A3)} Inhibitor|{Anti-Mouse IFNAR1 Antibody (MAR1-5A3)} Epigenetics|{Anti-Mouse IFNAR1 Antibody (MAR1-5A3)} Protocol|{Anti-Mouse IFNAR1 Antibody (MAR1-5A3)} Formula|{Anti-Mouse IFNAR1 Antibody (MAR1-5A3)} custom synthesis} HER4.PMID:23577779 EGFR T790M/L858R and HER2, respectively. pan-HER-IN-1 induces apoptosis and shows antitumor activities !!).|Product information|CAS Number: 1639040-94-0|Molecular Weight: 408.25|Formula: C19H14BrN5O|Smiles: C=CC(=O)NC1=CC2=C(NC3C=C4C(Br)=CNC4=CC=3)N=CN=C2C=C1|InChiKey: ATUXFPJRTSKHFB-UHFFFAOYSA-N|InChi: InChI=1S/C19H14BrN5O/c1-2-18(26)24-11-3-6-17-14(8-11)19(23-10-22-17)25-12-4-5-16-13(7-12)15(20)9-21-16/h2-10,21H,1H2,(H,24,26)(H,22,23,25)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: To be determined|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|