Product Name :
Fabesetron
Description:
Fabesetron (FK1052) is an orally active 5-HT3 receptor antagonist with 5-HT4 receptor antagonistic activity. Fabesetron (FK1052) can be used in the study for both acute and delayed emesis induced by cancer chemotherapy.
CAS:
129300-27-2
Molecular Weight:
293.36
Formula:
C18H19N3O
Chemical Name:
(7R)-10-methyl-7-[(5-methyl-1H-imidazol-4-yl)methyl]-6H,7H,8H,9H-pyrido[1,2-a]indol-6-one
Smiles :
CC1C2=CC=CC=C2N2C(=O)[C@@H](CC3N=CNC=3C)CCC2=1
InChiKey:
AEKQMJRJRAHOAP-CYBMUJFWSA-N
InChi :
InChI=1S/C18H19N3O/c1-11-14-5-3-4-6-17(14)21-16(11)8-7-13(18(21)22)9-15-12(2)19-10-20-15/h3-6,10,13H,7-9H2,1-2H3,(H,19,20)/t13-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Tucatinib} medchemexpress|{Tucatinib} EGFR|{Tucatinib} Protocol|{Tucatinib} In Vitro|{Tucatinib} supplier|{Tucatinib} Autophagy}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Bulevirtide} MedChemExpress|{Bulevirtide} HBV|{Bulevirtide} Technical Information|{Bulevirtide} Purity|{Bulevirtide} custom synthesis|{Bulevirtide} Epigenetic Reader Domain}
Additional information:
Fabesetron (FK1052) is an orally active 5-HT3 receptor antagonist with 5-HT4 receptor antagonistic activity.PMID:25040798 Fabesetron (FK1052) can be used in the study for both acute and delayed emesis induced by cancer chemotherapy.|Product information|CAS Number: 129300-27-2|Molecular Weight: 293.36|Formula: C18H19N3O|Chemical Name: (7R)-10-methyl-7-[(5-methyl-1H-imidazol-4-yl)methyl]-6H,7H,8H,9H-pyrido[1,2-a]indol-6-one|Smiles: CC1C2=CC=CC=C2N2C(=O)[C@@H](CC3N=CNC=3C)CCC2=1|InChiKey: AEKQMJRJRAHOAP-CYBMUJFWSA-N|InChi: InChI=1S/C18H19N3O/c1-11-14-5-3-4-6-17(14)21-16(11)8-7-13(18(21)22)9-15-12(2)19-10-20-15/h3-6,10,13H,7-9H2,1-2H3,(H,19,20)/t13-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Fabesetron (FK1052) (0.1 mg/kg p.o.) inhibits completely the increases in the colonic transit. FK1052 (100 µg/kg) completely prevents emesis induced by cisplatin (18 mg/kg, i.p.) in Suncus murinus.|Products are for research use only. Not for human use.|