Product Name :
Dynasore
Description:
Dynasore is a dynamin inhibitor (IC50 = 15 μM). dynasore inhibits bone resorption by rapidly disrupting actin rings of osteoclasts. Dynasore disrupts trafficking of herpes simplex virus proteins. Dynasore enhances the formation of mitochondrial antiviral signalling aggregates and endocytosis-independent NF-κB activation. Dynasore protects mitochondria and improves cardiac lusitropy in Langendorff perfused mouse heart. Dynasore impairs cholesterol trafficking and sterol-sensitive genes transcription in human HeLa cells and macrophages.
CAS:
304448-55-3
Molecular Weight:
322.31
Formula:
C18H14N2O4
Chemical Name:
N’-[(1E)-(3,4-dihydroxyphenyl)methylidene]-3-hydroxynaphthalene-2-carbohydrazide
Smiles :
OC1=CC(/C=N/NC(=O)C2=CC3=CC=CC=C3C=C2O)=CC=C1O
InChiKey:
SYNDQCRDGGCQRZ-VXLYETTFSA-N
InChi :
InChI=1S/C18H14N2O4/c21-15-6-5-11(7-17(15)23)10-19-20-18(24)14-8-12-3-1-2-4-13(12)9-16(14)22/h1-10,21-23H,(H,20,24)/b19-10+
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{iBRD4-BD1} medchemexpress|{iBRD4-BD1} Epigenetics|{iBRD4-BD1} Biological Activity|{iBRD4-BD1} In stock|{iBRD4-BD1} manufacturer|{iBRD4-BD1} Autophagy}
Shelf Life:
≥360 days if stored properly.{{Roxithromycin} MedChemExpress|{Roxithromycin} Bacterial|{Roxithromycin} Technical Information|{Roxithromycin} References|{Roxithromycin} custom synthesis|{Roxithromycin} Epigenetic Reader Domain}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24516446
Additional information:
Dynasore is a dynamin inhibitor (IC50 = 15 μM). dynasore inhibits bone resorption by rapidly disrupting actin rings of osteoclasts. Dynasore disrupts trafficking of herpes simplex virus proteins. Dynasore enhances the formation of mitochondrial antiviral signalling aggregates and endocytosis-independent NF-κB activation. Dynasore protects mitochondria and improves cardiac lusitropy in Langendorff perfused mouse heart. Dynasore impairs cholesterol trafficking and sterol-sensitive genes transcription in human HeLa cells and macrophages.|Product information|CAS Number: 304448-55-3|Molecular Weight: 322.31|Formula: C18H14N2O4|Chemical Name: N’-[(1E)-(3,4-dihydroxyphenyl)methylidene]-3-hydroxynaphthalene-2-carbohydrazide|Smiles: OC1=CC(/C=N/NC(=O)C2=CC3=CC=CC=C3C=C2O)=CC=C1O|InChiKey: SYNDQCRDGGCQRZ-VXLYETTFSA-N|InChi: InChI=1S/C18H14N2O4/c21-15-6-5-11(7-17(15)23)10-19-20-18(24)14-8-12-3-1-2-4-13(12)9-16(14)22/h1-10,21-23H,(H,20,24)/b19-10+|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|