Product Name :
BML-190
Description:
BML-190, also known as IMMA and LM-4131 or Indomethacin Morpholinylamide, is selective CB2 receptor agonist. The binding constant for the CB2 receptor is 435 nM compared to >20,000 nM for the cannabinoid receptor, CB1. BML-190 reduces the basal levels of inositol phosphate production in cells expressing the CB(2) receptor and 16z44. BML-190 acts as inverse agonist at the human CB(2) receptor acting via G alpha(i/o) and G alpha(q) family-coupled pathways.
CAS:
2854-32-2
Molecular Weight:
426.89
Formula:
C23H23ClN2O4
Chemical Name:
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-1-(morpholin-4-yl)ethan-1-one
Smiles :
CC1=C(CC(=O)N2CCOCC2)C2=CC(=CC=C2N1C(=O)C1C=CC(Cl)=CC=1)OC
InChiKey:
BJSDNVVWJYDOLK-UHFFFAOYSA-N
InChi :
InChI=1S/C23H23ClN2O4/c1-15-19(14-22(27)25-9-11-30-12-10-25)20-13-18(29-2)7-8-21(20)26(15)23(28)16-3-5-17(24)6-4-16/h3-8,13H,9-12,14H2,1-2H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
BML-190, also known as IMMA and LM-4131 or Indomethacin Morpholinylamide, is selective CB2 receptor agonist. The binding constant for the CB2 receptor is 435 nM compared to >20,000 nM for the cannabinoid receptor, CB1.{{Cholesterol} web|{Cholesterol} Bacterial|{Cholesterol} Purity & Documentation|{Cholesterol} Description|{Cholesterol} manufacturer|{Cholesterol} Autophagy} BML-190 reduces the basal levels of inositol phosphate production in cells expressing the CB(2) receptor and 16z44.{{Moxetumomab} site|{Moxetumomab} Immunology/Inflammation|{Moxetumomab} Technical Information|{Moxetumomab} In Vivo|{Moxetumomab} custom synthesis|{Moxetumomab} Autophagy} BML-190 acts as inverse agonist at the human CB(2) receptor acting via G alpha(i/o) and G alpha(q) family-coupled pathways.PMID:24406011 |Product information|CAS Number: 2854-32-2|Molecular Weight: 426.89|Formula: C23H23ClN2O4|Chemical Name: 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-1-(morpholin-4-yl)ethan-1-one|Smiles: CC1=C(CC(=O)N2CCOCC2)C2=CC(=CC=C2N1C(=O)C1C=CC(Cl)=CC=1)OC|InChiKey: BJSDNVVWJYDOLK-UHFFFAOYSA-N|InChi: InChI=1S/C23H23ClN2O4/c1-15-19(14-22(27)25-9-11-30-12-10-25)20-13-18(29-2)7-8-21(20)26(15)23(28)16-3-5-17(24)6-4-16/h3-8,13H,9-12,14H2,1-2H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|