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NIH Public AccessAuthor ManuscriptAnesthesiology. Author manuscript; obtainable in PMC 2014 November 01.Published in final edited form as: Anesthesiology. 2013 November ; 119(five): 1006008. doi:ten.1097/ALN.0b013e3182a8a90c.NIH-PA Author Manuscript NIH-PA Author Manuscript NIH-PA Author ManuscriptExome Sequencing: A single Little Step for Malignant Hyperthermia, One particular Giant Step for Our Specialty:Why exome sequencing matters to all of us, not only the professionals Peter Nagele, MD, MSc Dept of Anesthesiology and Genetics, Washington University School of Medicine, 660 S.PMID:23381601 Euclid Ave, Box 8054, St. Louis, MO 63110, [email protected]; phone: 314-362-5129; fax: 314-362-1185 One particular hundred years ago, the conventional globe hitherto identified to physicists ceased to exist. Inside the time span of a generation, the foundations of classical mechanics were shattered by Einstein’s theory of relativity and quantum mechanics. A brand new era as well as the Golden Age of New Physics began. A single hundred years later nowadays a comparable revolution is taking place and this time in medicine. Yet, couple of practicing physicians inside and outside our specialty are aware of.