Name : Exodus-2/CCL21, Human
Product Concentration :
Background :
Exodus-2/CCL21 is a novel CC chemokine discovered independently by three groups from the EST database, and shows 21-33% identity to other CC chemokines. Exodus-2 contains the four conserved cysteines characteristic of β chemokines plus two additional cysteines in its unusually long carboxyl terminal domain. It is expressed in lymph nodes of certain endothelial cells, and in the spleen and appendix. Exodus-2 chemoattracts T and B lymphocytes and inhibits hematopoiesis.
Biological Activity :
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human lymphocytes is in a concentration range of 10.0-100.0 ng/ml.
expression system :
E. coli
Tag :
CCL21 (Ser24-Pro134)Accession # O00585
Protein Accession No. :
O00585
Synonyms :
6Ckine; CKb9; ECL; SCYA21; SLC; TCA4; C-C motif chemokine ligand 21
Molecular Weight :
Purity :
> 97% as analyzed by SDS-PAGE> 97% as analyzed by HPLC
Product Concentration :
Lyophilized from a 0.2 μm filtered solution in 20 mM PB, pH 7.4, 150 mM NaCl.
Storage and Stability :
Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles.
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