Name : MIF, Human
Product Concentration :
Background :
Macrophage Migration Inhibitory Factor (MIF) is a pleiotropic cytokine, existing as a homotrimer in vivo. MIF was originally identified as a T cell derived factor responsible for the inhibition of macrophage migration. However, recently MIF has received much more attention because of its possible roles in angiogenesis and cancer development. MIF is over-expressed in various cancers, including pancreatic, breast, colon, brain, prostate, skin, and lung. The intratumoral expression of MIF is strongly correlated with angiogenic growth factor expression, such as the expression of Interleukin 8 (IL-8) and Vascular Endothelial Growth Factor (VEGF), and with risk of recurrence after resection.
Biological Activity :
expression system :
E. coli
Tag :
MIF (Met1-Ala115)Accession # P14174
Protein Accession No. :
P14174
Synonyms :
Macrophage Migration; Inhibitory Factor; GLIF; MMIF; GIF; Glycosylation-inhibiting factor
Molecular Weight :
~12.5 kDa, on SDS-PAGE under reducing conditions.
Purity :
> 95% as analyzed by SDS-PAGE> 95% as analyzed by HPLC
Product Concentration :
Lyophilized after extensive dialysis against PBS.
Storage and Stability :
Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
TDT Protein
USP5 Protein
Popular categories:
Raf-1
Mitogen-Activated Protein Kinase 13 (p38 delta/MAPK13)