Name : IL-16, Human
Product Concentration :
Background :
IL-16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, human IL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4+ T cells. Human and murine IL-16 show significant cross-species reactivity.
Biological Activity :
expression system :
E. coli
Tag :
IL-16 (Met1203-Ser1332)Accession # Q14005
Protein Accession No. :
Q14005
Synonyms :
IL16; LCF; NPRprIL-16; IL-16; interleukin 16
Molecular Weight :
18-20 kDa, on SDS-PAGE under reducing conditions.
Purity :
> 95% as analyzed by SDS-PAGE
Product Concentration :
Lyophilized from a 0.2 μm filtered solution in 20 mM PB, 150 mM NaCl, pH 7.0.
Storage and Stability :
Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles.
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