Name : G-CSF, Human
Product Concentration :
Background :
Granulocyte Colony-Stimulating Factor (G-CSF) contains internal disulfide bonds. Among the family of colony-stimulating factors, Granulocyte Colony Stimulating Factor (G-CSF) is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of Granulocyte Colony Stimulating Factor (G-CSF) can be induced by bacterial endotoxins, TNF, Interleukin-1 and GM-CSF. Prostaglandin E2 inhibits the synthesis of Granulocyte Colony Stimulating Factor (G-CSF). In epithelial, endothelial, and fibroblastic cells secretion of Granulocyte Colony Stimulating Factor (G-CSF) is induced by Interleukin-17.
Biological Activity :
G-CSF, Human (Cat. No. Z02974) stimulates cell proliferation of M-NFS-60 cells. The ED50 for this effect is typically 20-100pg/mL. Biological ActivityG-CSF, Human (Cat. No. Z02974) stimulates cell proliferation of M-NFS-60 cells. The ED50 for this effect is typically 20-100pg/mL. G-CSF, Human Granulocyte Colony-Stimulating Factor (G-CSF) contains internal disulfide bonds. Among the family of colony-stimulating factors, Granulocyte Colony Stimulating Factor (G-CSF) is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of Granulocyte Colony Stimulating Factor (G-CSF) can be induced by bacterial endotoxins, TNF, Interleukin-1 and GM-CSF. Prostaglandin E2 inhibits the synthesis of Granulocyte Colony Stimulating Factor (G-CSF). In epithelial, endothelial, and fibroblastic cells secretion of Granulocyte Colony Stimulating Factor (G-CSF) is induced by Interleukin-17. .hide { display: none!important; } .product_table_cart_div{ width: 100%; } .product_table_cart_div .unit{ display: block; font-weight: bold; min-width: 120px; text-align: left; width: 100px; } .form-control{ width: 45px; height: 30px; line-height: 30px; display: inline; padding: 0px 0px 0px 5px; } .product_table_cart_div .size-box{ padding: 4px 5px; border: 1px solid #cccccc; text-align: center; margin-right: 10px; } .product_table_cart_div span{ color: black !important; } .product_table_cart_div .price{ font-weight: 600; font-style: normal; color: #1D73DD; font-size: 30px; text-align: left; color: #F41D27 !important; } .product_table_cart_div .price-td{ padding-bottom:50px !important; } .btn-add-to-cart .button-face{ height: 40px; font-size: 16px; } .size-list div{ display: inline-block; } .ask-us{ color: #1D73DD; margin: 0 10px; } .btn-add-to-cart{ width: 180px; }
expression system :
E. coli
Tag :
Expressed with an N-terminal Met. G-CSF (Thr27-Pro200)Accession # Q8N4W3
Protein Accession No. :
Q8N4W3
Synonyms :
CSF3; C17orf33; CSF3OS; GCSF; colony stimulating factor 3; CSF-3; Granulocyte Colony-Stimulating Factor
Molecular Weight :
~18.8 kDa, on SDS-PAGE under reducing conditions.
Purity :
> 95% as analyzed by SDS-PAGE> 95% as analyzed by HPLC
Product Concentration :
Lyophilized after extensive dialysis against 25 mM Tris, pH 8.0.
Storage and Stability :
Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.
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