Name : IFN-γ, Mouse
Product Concentration :
Background :
Sharing 41% sequence identity with human Interferon gamma (hIFN–γ), mouse IFN gamma (mIFN–γ)is a macrophage-activating factor.The active form of IFN–γ is an antiparallel dimer that sets off IFN–γ/JAK/STAT pathway. IFN–γ signaling does diverse biological functions primarily related to host defense and immune regulation, including antiviral and antibacterial defense, apoptosis, inflammation, and innate and acquired immunity.While IFN–γ–induced inflammatory cascade summons a variety of immune-related cell types, such as macrophages, natural killer (NK) cells and cytotoxic T lymphocytes (CTLs), IFN–γ is also implicated in resistance to NK cell and CTL responses and in immune escape in avariety of cancers.
Biological Activity :
ED50
expression system :
E. coli
Tag :
Expressed with an N-terminal Met. IFN-γ (His23-Cys155)Accession # P01580
Protein Accession No. :
P01580
Synonyms :
Immune Interferon; type II interferon; T cell interferon; MAF; IFNG; IFG; IFI; IFN-gamma
Molecular Weight :
~15 kDa, on SDS-PAGE under reducing conditions.
Purity :
> 95% as analyzed by SDS-PAGE
Product Concentration :
Lyophilized after extensive dialysis against PBS.
Storage and Stability :
Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.
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