Recombinant Human RANTES (CCL5)
RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant human RANTES is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines. AF38472
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Source: |
E. Coli
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Purity:
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Above 98% as determined by SDS-PAGE Analysis.
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Cross Reactivity: |
Bacteria, Cow, Hamster, Monkey, Mouse, Rat
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Biological Activity
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Determined by its ability to chemoattract human blood monocytes using a concentration range of 1.0-10.0 ng/ml.
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AA Sequence
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SPYSSDTTP CCFAYIARP LPRAHIKEY FYTSGKCSN PAVVFVTRK NRQVCANPE KKWVREYIN SLEMS
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| Research Interest: | , , , Inflammation, |
| Protein Cross Reactivity: | Bacteria, Cow, Hamster, Monkey, Mouse, Rat |