Recombinant Human GRO/MGSA (CXCL1)
All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. GRO/MGSA also stimulates mitogenesis in certain human melanoma cells. Recombinant human GRO/MGSA is a 7.8 kDa protein consisting of 73 amino acids including the ELR motif common to the CXC chemokine family that bind to CXCR1 or CXCR2. Reparixin (L-lysine salt)
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Source: |
E. Coli
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Purity:
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Above 98% as determined by SDS-PAGE Analysis.
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Cross Reactivity: |
Bacteria, Hamster, Monkey,Mouse, Rat
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Biological Activity
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Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-50.0 ng/ml.
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AA Sequence
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ASVATELRC QCLQTLQGI HPKNIQSVN VKSPGPHCA QTEVIATLK NGRKACLNP ASPIVKKII EKMLNSDKS N
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| Research Interest: | , , , Inflammation, |
| Protein Cross Reactivity: | Bacteria, Hamster, Monkey,Mouse, Rat |