Anti-Mouse CD81 SAFIRE Purified
The Eat-2 monoclonal antibody reacts with mouse CD81, a 26kDA non-glycosylated transmembrane protein. CD81 is expressed broadly on B cells, T cells, NK cells, dendritic cells, fibroblasts, and endothelial cells. It plays a role in T cell development and is involved in B and T cell adhesion. The Eat-2 antibody is also reported to cross-react with the rat CD81 antigen. MLN4924
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Clone
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EAT-2 (Eat2)
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Format: |
SAFIRE Purified
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Applications
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FC, IP, WB
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Reactivity
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Mouse, Rat
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Isotype:
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Armenian Hamster IgG
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| Cell Type: | , , , |
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Preperation:
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The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
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Formulation:
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Phosphate-buffered aqueous solution, ph7.2.
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References:
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Miyazaki, T., Müller, U., & Campbell, K. S. (1997). Normal development but differentially altered proliferative responses of lymphocytes in mice lacking CD81. The EMBO journal, 16(14), 4217-4225. Boismenu, R., Rhein, M., Fischer, W. H., & Havran, W. L. (1996). A role for CD81 in early T cell development. Science, 271(5246), 198-200. Maecker, H. T., Todd, S. C., Kim, E. C., & Levy, S. (2000). Differential expression of murine CD81 highlighted by new anti-mouse CD81 monoclonal antibodies. Hybridoma, 19(1), 15-22. |