Anti-Mouse CD339 (Jagged 1) PE
The HMJ1-29 monoclonal antibody reacts with mouse and rat CD339 (Jagged 1), a type 1 transmembrane Notch receptor ligand. It is expressed by macrophages and certain stromal, epithelial, dendritic, and thymic lymphoid cells. It has been reported to be play a role in Treg induction, Th2 polarization, neurogenesis, and cardiovascular development. THZ2 (Hydrochloride)
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Clone
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HMJ1-29
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Format: |
PE
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Applications
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FC
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Reactivity
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Mouse, Rat
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Isotype:
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Armenian Hamster IgG
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Preperation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Sekine, C., Moriyama, Y., Koyanagi, A., Koyama, N., Ogata, H., Okumura, K., & Yagita, H. (2009). Differential regulation of splenic CD8− dendritic cells and marginal zone B cells by Notch ligands. International immunology, 21(3), 295-301. Yamaguchi, E., Chiba, S., Kumano, K., Kunisato, A., Takahashi, T., Takahashi, T., & Hirai, H. (2002). Expression of Notch ligands, Jagged1, 2 and Delta1 in antigen presenting cells in mice. Immunology letters, 81(1), 59-64. Elyaman, W., Bradshaw, E. M., Wang, Y., Oukka, M., Kivisäkk, P., Chiba, S., … & Khoury, S. J. (2007). JAGGED1 and delta1 differentially regulate the outcome of experimental autoimmune encephalomyelitis. The Journal of Immunology, 179(9), 5990-5998. |