Anti-Mouse CD31 Purified
The 390 monoclonal antibody specifically reacts with mouse cd31, a 130-140 kDA type I transmembrane glycoprotein also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1). CD31 is reported to bind to CD38 and is expressed on platelets, monocytes, granulocytes, and endothelial cells. It plays a role in angiogenesis, wound healing, cellular migration, and signal transduction. RN486
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Clone
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390
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Format: |
Purified
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Applications
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FC, IHC, IHP
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Reactivity
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Mouse
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Isotype:
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Rat IgG2a, kappa
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| Research Interest: | |
| Cell Type: | , , , |
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Preperation:
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The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2
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References:
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HORENSTEIN, A., STOCKINGER, H., Imhof, B., & MALAVASI, F. (1998). CD38 binding to human myeloid cells is mediated by mouse and human CD31.Biochem. J, 330, 1129-1135. Baldwin, H. S., Shen, H. M., Yan, H. C., DeLisser, H. M., Chung, A., Mickanin, C., … & Albelda, S. M. (1994). Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development. Development, 120(9), 2539-2553. DeLisser, H. M., Christofidou-Solomidou, M., Strieter, R. M., Burdick, M. D., Robinson, C. S., Wexler, R. S., … & Albelda, S. M. (1997). Involvement of endothelial PECAM-1/CD31 in angiogenesis. The American journal of pathology, 151(3), 671. |