Anti-Mouse CD144 (VE-Cadherin) PE
The BV13 monoclonal antibody specifically reacts with mouse CD144 (VE-Cadherin), a 120 kDA type II Cadherin. CD144 is a hemophilic adhesion molecule of the endothelial cell line essential to maintaining cell layer integrity. It is involved in cell growth inhibition, migration, and survival. Fulvestrant
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Clone
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BV13
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Format: |
PE
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Applications
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FC
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Reactivity
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Mouse
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Isotype:
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Rat IgG1, kappa
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Preperation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Corada, M., Mariotti, M., Thurston, G., Smith, K., Kunkel, R., Brockhaus, M., … & Dejana, E. (1999). Vascular endothelial–cadherin is an important determinant of microvascular integrity in vivo. Proceedings of the National Academy of Sciences, 96(17), 9815-9820. Crosby, C. V., Fleming, P. A., Argraves, W. S., Corada, M., Zanetta, L., Dejana, E., & Drake, C. J. (2005). VE-cadherin is not required for the formation of nascent blood vessels but acts to prevent their disassembly. Blood, 105(7), 2771-2776. May, C., Doody, J. F., Abdullah, R., Balderes, P., Xu, X., Chen, C. P., … & Bohlen, P. (2005). Identification of a transiently exposed VE-cadherin epitope that allows for specific targeting of an antibody to the tumor neovasculature.Blood, 105(11), 4337-4344. |